数字减影血管造影引导下经鞘管内钳夹活检辅助诊断肺动脉梗阻性疾病  

Trans-sheath intraluminal forceps biopsy under digital subtraction angiography guidance for assisting diagnosis of pulmonary artery obstructive diseases

作　　者：侯荣娜 周学良[1] 宋梦瑶 张程智 孙占国 方毅[1] 韩新巍[1] 焦德超[1] HOU Rongna;ZHOU X ueliang;SONG Mengyao;ZHANG C hengzhi;SUN Z hanguo;FANG Yi;HAN X inwei;JIAO Dechao(Department of Interventional Radiology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院放射介入科,河南郑州450052

出　　处：《中国介入影像与治疗学》2024年第7期390-392,共3页Chinese Journal of Interventional Imaging and Therapy

摘　　要：目的 观察数字减影血管造影(DSA)引导下经鞘管内钳夹活检辅助诊断肺动脉梗阻性疾病的有效性及其安全性。方法 回顾性分析16例因肺动脉梗阻性疾病而接受经股静脉途径钳夹活检患者资料,记录其临床表现,以取材满足病理学诊断所需为技术成功;根据病理学结果诊断恶性病变,将活检病理为良性且其后半年及以上病情无明显变化,或手术病理良性者归为良性病变,二者均不符合为“未确诊”。记录钳夹活检操作时间、技术成功率、诊断效能、并发症及活检前、后肺动脉压改变。结果 16例中,9例表现为间断胸闷、4例胸痛伴胸闷、2例胸痛、1例无明显症状;10例病灶位于左肺、6例位于右肺,增强CT显示病变肺动脉内存在充盈缺损。对16例共行16次钳夹活检,平均操作时间(31.02±6.02)min,技术成功率100%。10例恶性肿瘤中,1例肺癌钳夹活检结果呈假阴性;6例良性病变中,钳夹活检均正确诊断。活检后2例出现一过性胸痛伴胸闷加重,均经对症治疗后缓解。活检前[(53.38±14.28)mmHg]、后[(53.69±14.15)mmHg]肺动脉压差异无统计学意义(P>0.05)。结论 DSA引导下经鞘管内钳夹活检能安全、有效地辅助诊断肺动脉梗阻性疾病。Objective To explore the efficiency and safety of trans-sheath intraluminal forceps biopsy under digital subtraction angiography(DSA)guidance for assisting diagnosis of pulmonary artery obstructive diseases.Methods Data of 16 patients who underwent trans-sheath intraluminal forceps biopsy for pulmonary artery obstructive diseases were retrospectively analyzed,and the clinical manifestations were recorded.The technical success of biopsy was defined as tissue obtained met the needs of pathology diagnosis.For patients with malignant pathology results,the final diagnosis was malignant,for those with benign pathology results after biopsy and no obvious changes after 6-month or longer follow-up,or benign pathology results after surgical resection,the final diagnosis was benign,otherwise was no clear diagnosis.The operation time,technical success rate,diagnostic efficiency,complications and changes of pulmonary artery pressure before and after the biopsy were observed.Results Among 16 patients,9 complained of intermittent chest tightness,4 complained of chest pain with chest tightness,2 complained of chest pain but 1 denied any symptoms.The lesions located in the left lung in 10 cases and in the right lung in 6 cases,all with enhanced CT showed filling defects of the involved branch of pulmonary artery.Totally 16 trans-sheath intraluminal forceps biopsies were performed in 16 patients,with an average operation time of(31.02±6.02)min and technical success rate of 100%.Malignant tumors were finally diagnosed in 10 cases,including 1 case of lung cancer with false-negative biopsy result,while biopsy correctly diagnosed benign lesions in the other 6 cases.Transient worsening chest pain with chest tightness occurred in 2 cases and relieved after symptomatic treatments.No statistically significant difference of pulmonary artery pressure was found before([53.38±14.28]mmHg)and after([53.69±14.15]mmHg)biopsy(P>0.05).Conclusion DSA-guided trans-sheath intraluminal forceps biopsy was relatively safe and valuable for assisting di

关 键 词：肺动脉 血管造影术 数字减影 活组织检查 

分 类 号：R543.5[医药卫生—心血管疾病] R815[医药卫生—内科学]