2008—2022年盐田区性传播疾病年龄、时期、队列分析  

Age-,period-and cohort-specific incidence of sexually transmitted diseases in Yantian District from 2008 to 2022

作　　者：林凯[1] 刘雅文 罗诗丽 李衡[1] 李雪梅[1] LIN Kai;LIU Yawen;LUO Shili;LI Heng;LI Xuemei(Department of Communicable Disease Control and Prevention,Yantian District Center for Disease Control and Prevention,Shenzhen,Guangdong 518000,China)

机构地区：[1]深圳市盐田区疾病预防控制中心传染病防制科,广东深圳518000

出　　处：《预防医学》2024年第7期584-589,共6页CHINA PREVENTIVE MEDICINE JOURNAL

摘　　要：目的 分析2008—2022年广东省深圳市盐田区性传播疾病发病率变化趋势,以及年龄、时期和队列因素对性传播疾病发病率的影响,为预防和控制性传播疾病提供依据。方法 通过中国疾病预防控制信息系统收集2008—2022年盐田区15~64岁梅毒、淋病、生殖道沙眼衣原体感染、尖锐湿疣和生殖器疱疹病例资料,描述性分析发病时间和人群分布;采用平均年度变化百分比(AAPC)分析发病趋势;采用年龄-时期-队列模型分析年龄、时期和队列对性传播疾病发病率的影响。结果 2008—2022年盐田区报告15~64岁性传播疾病6 156例,年均发病率为229.92/10万,发病率呈上升趋势(AAPC=2.409%,P<0.05),其中女性发病率上升趋势明显(AAPC=5.846%,P<0.05),男性发病率未见明显变化(AAPC=0.193%,P>0.05)。年龄-时期-队列模型分析结果显示,性传播疾病发病率随年龄增长呈先上升后下降趋势,男性发病率变化趋势与全人群一致,峰值为30~34岁组的371.04/10万;女性发病率随年龄增长呈上升趋势,峰值为60~64岁组的442.15/10万。以2013—2017年为对照时期,2018—2022年性传播疾病发病风险增加(RR=1.349,95%CI:1.217~1.495);以1975—1979年出生队列为对照队列,1980—2004年出生队列发病风险呈上升趋势,2000—2004年出生队列发病风险最高(RR=4.178,95%CI:2.717~6.423)。结论 2008—2022年盐田区15~64岁人群性传播疾病发病率呈上升趋势,年龄、时期和队列对发病率均有影响,对女性的影响大于男性。Objective To investigate the incidence trend of sexually transmitted diseases(STDs)in Yantian District,Shenzhen City,Guangdong Province from 2008 to 2022,and the effects of age,period,and cohort on STDs incidence,so as to provide the basis for formulating control measures for STDs.Methods Data of reported STDs cases(syphilis,gonorrhea,genital Chlamydia trachomatis infections,condyloma acuminatum and genital herpes)among population aged 15 to 64 years in Yantian District from 2008 to 2022 were collected through the Chinese Disease Control and Prevention Information System.The temporal and population distribution of STDs were descriptively analyzed.Trends in incidence of STDs were analyzed using average annual percent change(AAPC).Impacts of age,period and cohort on the incidence of STDs were analyzed by an age-period-cohort model.Results A total of 6156 cases of STDs aged 15 to 64 years were reported from 2008 to 2022,and the average annual incidence was 229.92/105.The overall incidence showed an upward trend(AAPC=2.409%,P<0.05),and an upward trend among females(AAPC=5.846%,P<0.05),but the trend was not statistically significant among males(AAPC=0.193%,P>0.05).The incidence of STDs showed an increasing trend followed by a decreasing trend with the increase of age.The incidence trend among males was consistent with the overall population,reaching its peak in the age group of 30 to 34 years(371.04/105),while the incidence among females showed an increasing trend with the increase of age,peaking in the age group of 60 to 64 years(442.15/105).Compared with 2013-2017,the incidence risk of STDs showed an increasing trend in 2018-2022(RR=1.349,95%CI:1.217-1.495).Compared with the birth cohort of 1975-1979,the incidence risk of STDs in 1980-2005 birth cohort showed an increasing trend,with the highest incidence risk in 2000-2004 birth cohort(RR=4.178,95%CI:2.717-6.423).Conclusions The overall incidence of STDs among residents aged 15 to 64 years in Yantian District from 2008 to 2022 appeared a tendency towards a rise.Age,

关 键 词：性传播疾病 发病率 年龄-时期-队列模型 

分 类 号：R512.63[医药卫生—内科学]