4例行左心室辅助装置植入术患者的围术期抗栓治疗分析  

Analysis and Monitoring of Perioperative Antithrombotic Therapy in 4 Patients Undergoing Left Ventricular Assist Device Implantation

作　　者：史金平 王立珍 张琰 唐亚娟 路小寒 白娟 洪术霞 SHI Jinping;WANG Lizhen;ZHANG Yan;TANG Yajuan;LU Xiaohan;BAI Juan;HONG Shuxia(Department of Pharmacy,Xi’an International Medical Center Hospital,Xi’an 710100,China)

机构地区：[1]西安国际医学中心医院药学部,西安710100

出　　处：《药学与临床研究》2024年第3期267-269,共3页Pharmaceutical and Clinical Research

基　　金：西安国际医学中心医院青年课题(2023QN13)。

摘　　要：临床药师通过监护4例既往长期抗血栓治疗,拟行左心室辅助装置植入术患者的围术期抗血栓治疗,旨在总结该类患者围术期抗血栓治疗的监护重点。结果提示,临床药师以术前讨论的方式,评估患者血栓与出血风险,制定手术前抗血栓药物的停药与桥接时机,且通过药学监护,调整术后抗血栓药物的剂量与给药时机,识别药物相互作用,可降低患者围术期血栓与出血事件发生率。Clinical pharmacists monitored perioperative antithrombotic therapy in four patients who underwent left ventricular assist device implantation after long-term anticoagulation therapy,aiming to summarize the focus of perioperative antithrombotic therapy in this patient population.The results revealed that clinical pharmacists assessed the thrombotic and bleeding risks of patients through preoperative discussions,determined the timing of discontinuing antithrombotic medications and bridging therapy before surgery,and adjusted the dosage and administration timing of postoperative antithrombotic medications through pharmaceutical monitoring,they also identified drug interactions,which reduced the incidence of perioperative thrombotic or bleeding events in patients.

关 键 词：左心室辅助装置 人工心脏 围手术期 抗凝管理 药学监护 

分 类 号：R969.3[医药卫生—药理学]