连云港市妇幼保健院产科超说明书用药现状分析及管理  

Analysis and management of off-label drug use in obstetrics Department of Lianyungang Maternal and Child Health Hospital

作　　者：高雪 杨静[1] 宋和娣[1] 崔爱瑛[1] GAO Xue;YANG Jing;SONG Hedi;CUI Aiying(Department of Pharmacy,Lianyungang Maternal and Child Health Care Hospital,Lianyungang 222006,China)

机构地区：[1]连云港市妇幼保健院药学部,连云港222006

出　　处：《药学与临床研究》2024年第3期270-273,共4页Pharmaceutical and Clinical Research

基　　金：江苏省药学会-奥赛康医院药学科研项目(A202147)。

摘　　要：为促进产科合理用药,降低孕产妇用药风险,现抽取连云港市妇幼保健院产科2021年1~6月门诊处方8733张和住院病历4812份,超说明书用药点评和循证医学证据评价结果显示:门诊处方超说明书用药1074张(12.30%),其中不合理处方89张(8.29%);住院病历超说明书用药2993份(62.20%),其中不合理898份(30.00%);超说明书用药药品有20种,其中16种有循证医学证据支持。制定并实施《超说明书用药管理规定及程序》和超说明书用药备案审核流程后,对2022年1~6月的门诊处方和住院病历进行点评,结果显示超说明书用药不合理比例均下降,分别为2.51%(31/1235)和9.03%(182/2016)。In order to promote rational medication in obstetrics and reduce medication risks for pregnant and postpartum women,8733 outpatient prescriptions and 4812 inpatient medical records were selected from the Obstetrics Department of Lianyungang Maternal and Child Health Hospital from January to June 2021.The results of review on off-label drug use and evidence-based medicine evaluation showed that 1074 outpatient prescriptions were off-label drug use(12.30%),including 89 unreasonable prescriptions(8.29%);2993 cases(62.20%)of inpatient medical records were off-label drug use,of which 898 cases(30.00%)were unreasonable;There were 20 types of drugs that were off-label drug use,of which 16 were supported by evidence-based medicine.After the formulation and implementation of the“Regulations and Procedures for the Management of Off-label Drug Use”and the review process for off-label drug use,the re-evaluation results from January to June 2022 showed that the unreasonable proportion of outpatient prescriptions and inpatient medical records for off-label drug use decreased to 2.51%(31/1235)and 9.03%(182/2016),respectively.

关 键 词：产科 超说明书用药 管理策略 

分 类 号：R969.3[医药卫生—药理学]