潜分类增长模型在获得性免疫缺陷综合征动态防控策略中的应用进展  

Application progress of latent class growth models in dynamic prevention and control strategies for acquired immunodeficiency syndrome

作　　者：翟咪咪 李亚敏[1,2] 刘苏顺 李云霞 刘义婷 李莉 雷先阳[5] ZHAI Mimi;LI Yamin;LIU Sushun;LI Yunxia;LIU Yiting;LI Li;LEI Xianyang(Clinical Nursing Teaching and Research Section,Second Xiangya Hospital,Central South University,Changsha 410011;Xiangya School of Nursing,Central South University,Changsha 410013;Department of General Surgery,Second Xiangya Hospital,Central South University,Changsha 410011;Department of Urology,First Affiliated Hospital of Xinjiang Medical University,Urumqi 830091;Xiangya School of Public Health,Central South University,Changsha 410013,China)

机构地区：[1]中南大学湘雅二医院临床护理教研室,长沙410011 [2]中南大学湘雅护理学院,长沙410013 [3]中南大学湘雅二医院普外科,长沙410011 [4]新疆医科大学附属第一医院泌尿外科,乌鲁木齐830091 [5]中南大学湘雅公共卫生学院,长沙410013

出　　处：《中南大学学报（医学版）》2024年第4期621-627,共7页Journal of Central South University ：Medical Science

基　　金：湖南省重点研发计划项目(2021SK2031);中南大学中央高校基本科研业务费专项资金(2023ZZTS0851)。

摘　　要：在不同群体中获得性免疫缺陷综合征(以下简称“艾滋病”)的防控需求具有显著的异质性,这为制订和实施防控策略带来了极大挑战。动态评估不同群体的异质性和疾病进展轨迹至关重要。潜分类增长模型是将纵向数据拟合为不同发展轨迹的N个亚组,以识别和分析不同亚组的发展轨迹,从而为疾病的防控策略提供新视角。潜分类增长模型在艾滋病防控领域的应用中显现出显著优势,尤其在深入理解和分析艾滋病流行病学特征、风险行为、心理研究、检测的异质性和动态变化等方面,总结其优势和局限可为艾滋病的精准防控提供科学依据。The prevention and control requirements for HIV/AIDS vary significantly among different populations,posing substantial challenges to the formulation and implementation of intervention strategies.Dynamically assessing the heterogeneity and disease progression trajectories of various groups is crucial.Latent class growth model(LCGM)serves as a statistical approach that fits a longitudinal data into N subgroups of individual development trajectories,identifying and analyzing the progression paths of different subgroups,thereby offering a novel perspective for disease control strategies.LCGM has shown significant advantages in the application of HIV/AIDS prevention and control,especially in gaining a deeper understanding and analysis of epidemiological characteristics,risk behaviors,psychological research,heterogeneity in testing,and dynamic changes.Summarizing the advantages and limitations of applying LCGM can provide a reliable basis for precise prevention and control of HIV/AIDS.

关 键 词：潜分类增长模型 获得性免疫缺陷综合征 预防控制 应用进展 

分 类 号：R512.91[医药卫生—内科学] R183[医药卫生—临床医学]