Solar Energy for Value-Added Chemical Production by LightPowered Microbial Factories  

作　　者：Haibo Wu Xilong Feng Liangjun Wang Cheng Chen Peng Wu Linpo Li Jinjie Xu Fan Qi Suoying Zhang Fengwei Huo Weina Zhang 

机构地区：[1]Key Laboratory of Flexible Electronics(KLOFE),Institute of Advanced Materials(IAM),School of Flexible Electronics(Future Technologies),Nanjing Tech University(NanjingTech),Nanjing 211816

出　　处：《CCS Chemistry》2024年第7期1776-1788,共13页中国化学会会刊（英文）

基　　金：supported by the National Natural Science Foundation of China (grant nos.21727808,21971114,and 21908105);the Natural Science Foundation of Jiangsu Province (grant no.BK20200090);the National Science Fund for Distinguished Young Scholars (grant no.21625401).

摘　　要：The light-driven material-microorganism biohybrid system has the potential to transfer solar energy for chemical production.However,few studies have reported the construction of biohybrid systems using light-responsive materials with nonmodel strains that have been widely used in practical industrial production for value-added chemicals,especially with regard to the mechanism of action of photogenerated charges in the cytoplasm,probably due to the complexity of their anabolic pathways.Herein,a biohybrid system as a research mode was constructed by electrostatically self-assembling a highly efficient light-harvesting material of graphite-phase nitrided carbon(g-C_(3)N_(4))nanosheets with nonmodel strains(Phaffia rhodozyma)for synthesis of nutritional chemical astaxanthin.The biohybrid interface enabled efficient separation,transfer,and transport of photogenerated charges from g-C_(3)N_(4) into the interior of P.rhodozyma,which improved the substance metabolism and the energy metabolism of P.rhodozyma.Notably,photogenerated charges can significantly promote the accumulation of precursors along the astaxanthin anabolic pathway and enhance the cytoplasmic redox environment and ATP levels in the interior of P.rhodozyma,even under adverse conditions(such as enzyme inhibitors),thus increasing the yield of astaxanthin compared to the traditional culture of P.rhodozyma.This study not only provides new ideas for converting solar energy into value-added chemicals,but it also provides guidance for regulating microbial synthesis plants.

关 键 词：biohybrid system light-driven graphitephase nitrided carbon Phaffia rhodozyma ASTAXANTHIN 

分 类 号：O64[理学—物理化学]