Photoelectrochemical Iron-Catalyzed C(sp^(3))-H Borylation of Alkanes in a Position-Selective Manner  

作　　者：Wen Wei Bin Wang Simon L.Homölle Jinbin Zhu Yanjun Li Tristan von Münchow Isaac Maksso Lutz Ackermann 

机构地区：[1]Institut für Organische und Biomolekulare Chemie,Georg-August-Universität Göttingen,37077 Göttingen

出　　处：《CCS Chemistry》2024年第6期1430-1438,共9页中国化学会会刊（英文）

基　　金：the European Research Council(ERC Advanced Grant;no.101021358);the Deutsche Forschungsgemeinschaft(DFG,Gottfried Wilhelm Leibniz award to L.A.);the Fonds der Chemischen Industrie(FCI,Kekulé-Fellowship to T.v.M.);the China Scholarship Council(CSC grant no.201906280067 to W.W.).

摘　　要：Catalytic C-H borylation is of prime topical importance,since easily available feedstock chemicals can thereby be transformed into valuable transient functional groups in the absence of directing groups.Herein,we disclose an iron-catalyzed C(sp^(3))-H borylation of simple,non-prefunctionalized alkanes,providing access to value-added products in a single step by means of photoelectrochemistry.The power of merging photo-and electrochemistry was mirrored by ample scope and exceedingly mild reaction conditions.Moreover,an outstanding position-selectivity in favor of primary C(sp^(3))-H proved viable within the photoelectrochemical borylation through a chemo-selective anodic overoxidation manifold.The ferro-photoelectrochemistry strategy avoids toxic precious transition metals,enabling C(sp^(3))-H borylations in a site-selective fashion.

关 键 词：PHOTOELECTROCATALYSIS C(sp^(3))-H borylation iron catalysis position-selectivity chlorine radical 

分 类 号：O62[理学—有机化学]