Electric-Induced Cycloelimination for Simulating Structural Plasticity in Organic Nociceptors  

作　　者：Zhiheng Zhu Kai Liu Haojie Huang Yangshuang Bian Mingcong Qin Chengyu Wang Wei Wen Mingliang Zhu Wenkang Shi Yanwei Liu Zhiyuan Zhao Huijuan Yan Hanlin Wang Yunqi Liu Yunlong Guo 

机构地区：[1]Beijing National Laboratory for Molecular Sciences,Key Laboratory of Organic Solids,Institute of Chemistry,Chinese Academy of Sciences,Beijing 100190 [2]University of Chinese Academy of Sciences,Beijing 100190

出　　处：《CCS Chemistry》2024年第6期1466-1476,共11页中国化学会会刊（英文）

基　　金：the National Key R&D Program(grant no.2018YFA0703200);the National Natural Science Foundation of China(grant nos.61890940 and 52003274);the Chinese Academy of Sciences(CAS)Project for Young Scientists in Basic Research(grant no.YSBR-053);the Strategic Priority Research Program of the CAS(grant no.XDB30000000);the CAS-Croucher Funding Scheme for Joint Laboratories,the CAS Cooperation Projects(grant no.121111KYSB20200036);Lu Jiaxi international team(grant no.GJTD-2020-02).

摘　　要：Continuous lifelong acquisition,updating,and finetuning of knowledge and skills is of crucial significance for the survival of humans.However,current neuromorphic devices exhibit obvious catastrophic forgetting when restimulated by new information.This remains a challenge for neuromorphic devices and artificial intelligence to achieve continuous learning.Herein,we propose an electric-induced cycloelimination strategy to realize an organic transistor nociceptor that can simulate synaptic and structural plasticity.The system benefits from the ring-opening characteristics of cross-linked poly(vinyl cinnamate)under a strong pulse voltage,during which new energy-level trap states are formed.The prepared organic transistor nociceptors exhibit both structural and synaptic plasticity.They simulate the characteristics of human nociceptors,including threshold,relaxation,sensitization,and maladaptation behavior.For the first time,we have simulated and explored the structural plasticity behavior in organisms based on electronic devices.More remarkably,the transistor nociceptors realize the reinput of information without forgetting the initial informa tion.The strategy developed for the preparation of organic transistor nociceptors provides insights for addressing the catastrophic forgetting in the lifelong learning of intelligent neuromorphic devices.

关 键 词：electric-induced cycloelimination structural plasticity organic nociceptors organic transistors METAPLASTICITY 

分 类 号：TN32[电子电信—物理电子学]