催产素与卡孕栓联合使用对顺产后产后出血的临床观察  

Clinical Observation of the Combination of Oxytocin and Suppository for Pregnancy in Treating Postpartum Hemorrhage after Natural Delivery

作　　者：张丝妮 Zhang Sini(Guangzhou Hospital of Integrated Traditional Chinese and Western Medicine,Guangzhou 510800,China)

机构地区：[1]广州市中西医结合医院,广东广州510800

出　　处：《哈尔滨医药》2024年第3期23-25,共3页Harbin Medical Journal

基　　金：广州市花都区科技计划项目(22-HDWS-060)。

摘　　要：目的探讨分析催产素与卡孕栓联合使用对顺产后产后出血的临床效果。方法选取120例顺产后产后出血产妇分为对照1组、对照2组、实验组,对照1组仅给予催产素治疗,对照2组仅给予卡孕栓治疗,实验组给予催产素与卡孕栓联合治疗,比较三组产妇出血量、止血时间、止血效果、凝血因子水平、不良反应。结果三组产妇产后出血量及止血时间差异有统计学意义(P<0.05),实验组产妇较对照1组、对照2组产妇产后出血量显著减少,止血时间显著缩短(P<0.05)。三组产妇止血效果总有效率差异有统计学意义(P<0.05),实验组产妇止血效果总有效率为97.50%较对照1组(65.00%)、对照2组(62.50%)显著提高(P<0.05)。治疗前三组产妇凝血因子Ⅶ、FIB、PTT、PT及PLT水平无显著性差异(P>0.05),治疗后三组产妇凝血因子Ⅶ、FIB、PTT、PT及PLT水平均显著改善,且治疗后实验组产妇凝血因子Ⅶ、FIB、PTT、PT及PLT水平较对照1组、对照2组产妇改善更显著(P<0.05)。实验组、对照1组、对照2组产妇服药期间不良反应发生率分别为10.00%、20.00%、17.50%,差异无统计学意义(P>0.05)。结论催产素与卡孕栓联合治疗产妇顺产后产后出血起到协同机制的作用,相互补充效果显著,可改善产妇凝血功能,缩短止血时间,安全性好,值得推广。Objective To investigate and analyze the clinical effect of combined use of oxytocin and pregnancy-suppository on postpartum hemorrhage after natural delivery.Methods A total of 120 cases of postpartum postpartum hemorrhage were selected and divided into control group 1,control group 2 and experimental group.Control group 1 only received oxytocin treatment,control group 2 only received pregnancy suppository treatment,and the experimental group received combined treatment with oxytocin and pregnancy suppository.The amount of blood loss,hemostatic time,hemostatic effect,coagulation factor level before and after treatment and the occurrence of adverse reactions were compared among the three groups.Results Postpartum blood loss and hemostatic time were significantly different among the three groups(P<0.05).Postpartum blood loss and hemostatic time were significantly reduced in the experimental group compared with control group 1 and control group 2(P<0.05).The total effective rate of hemostatic effect was significantly different among the three groups(P<0.05).The total effective rate of hemostasis in the experimental group was 97.50%,which was significantly higher than that in control group 1(65.00%)and control group 2(62.50%)(P<0.05).There were no significant differences in the levels of coagulation factorⅦ,FIB,PTT,PT and PLT in the three groups before treatment(P>0.05).The levels of coagulation factorⅦ,FIB,PTT,PT and PLT in the three groups were significantly improved after treatment,and the levels of coagulation factorⅦ,FIB,PTT,PT and PLT in the experimental group were more significantly improved than those in control group 1 and control group 2(P<0.05).The incidence of adverse reactions during medication in experimental group,control group 1 and control group 2 was 10.00%,20.00%and 17.50%,respectively,with no statistical significance(P>0.05).Conclusion The combination of oxytocin and pregnancy suppository plays a synergistic role in the treatment of postpartum postpartum hemorrhage,with significant compleme

关 键 词：催产素 卡孕栓 顺产 产后出血 

分 类 号：R714.461[医药卫生—妇产科学]