Genome editing enables defense-yield balance in rice  

作　　者：Yiwen Deng Zuhua He 

机构地区：[1]National Key Laboratory of Plant Molecular Genetics,CAS Center for Excellence in Molecular Plant Sciences,Institute of Plant Physiology and Ecology,Chinese Academy of Sciences,Shanghai,China

出　　处：《Stress Biology》2023年第1期250-253,共4页逆境生物学（英文）

基　　金：supported by grants from the National Natural Science Foundation of China(U20A2021,32088102 and 31720103913);the Strategic Priority Research Program of Chinese Academy of Sciences(XDA24010304 and XDB27040201).

摘　　要：This brief article highlights the key findings of the study conducted by Sha et al.(Nature,doi:10.1038/s41586-023-06205-2,2023),focusing on the cloning of the RBL1 gene from rice,which is associated with lesion mimic mutant(LMM)traits.The RBL1 gene encodes a cytidine diphosphate diacylglycerol(CDP-DAG)synthase and plays a crucial role in regulating cell death and immunity by controlling phosphatidylinositol biosynthesis.The rbl1 mutant shows autoimmunity with multi-pathogen resistance but with severe yield penalty.Using genome editing techniques,the research team successfully generated an elite allele of RBL1 that not only restores rice yield but also provides broad-spectrum resistance against both bacterial and fungal pathogens.These findings demonstrate the potential of utilizing genome editing to enhance crop productivity and pathogen resistance.

关 键 词：Lesion mimic mutant RICE Broad-spectrum resistance PHOSPHOLIPIDS Genome editing 

分 类 号：S511[农业科学—作物学]