MRI对2型糖尿病胰腺变化的研究价值  

Value of MRI in study of pancreatic changes in type 2 diabetes mellitu

作　　者：袁永丰[1] 王中秋[1] 杨梦 曾亮[1] 高希法 武惠明 YUAN Yongfeng;WANG Zhongqiu;YANG Meng;ZENG Liang;GAO Xifa;WU Huiming(Department of Radiology,Affiliated Hospital of Nanjing University of Traditional Chinese Medicine,Nanjing 210029,China;Department of Radiology,Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School,Nanjing University,Nanjing 210008,China)

机构地区：[1]南京中医药大学附属医院放射科,江苏南京210029 [2]南京大学医学院附属鼓楼医院影像科,江苏南京210008

出　　处：《中国中西医结合影像学杂志》2024年第4期434-438,444,共6页Chinese Imaging Journal of Integrated Traditional and Western Medicine

基　　金：国家自然科学基金项目(82171925);江苏省教育教学“十四五”规划2021年度高教重点课题(B/2021/01/44);江苏省中医院创新发展基金专项课题(Y2020CX08)。

摘　　要：目的:采用MRI多序列扫描,前瞻性研究2型糖尿病(T2DM)胰腺脂肪含量、胰腺体积(胰体比)和胰腺形态的变化,综合评估各影像指标与T2DM的相关性,总结T2DM胰腺变化的主要特征。方法:招募50例T2DM患者(T2DM组)和50例非糖尿病志愿者(对照组),均行上腹部MRI检查。测量并比较胰体比、胰腺脂肪含量及胰腺边缘形态分级。结果:T2DM组胰体比[(36.38±9.62)cm^(3)/m^(2)]小于对照组[(46.94±8.67)cm^(3)/m^(2)],差异有统计学意义(P<0.001);T2DM组胰腺脂肪含量[(6.17±2.89)%]大于对照组[(3.64±3.47)%],差异有统计学意义(P<0.05);T2DM组胰腺边缘形态分级(1.80±1.03)高于对照组(1.26±0.99),差异无统计学意义(P=0.440)。结论:T2DM患者主要表现为脂肪含量增加和胰腺体积缩小。MRI多序列扫描能精准评估T2DM患者的胰腺脂肪含量和胰腺体积的改变。Objective:To explore the changes of pancreatic fat content,pancreatic volume and pancreatic morphology in patients with type 2 diabetes mellitus(T2DM)by using MRI multi-sequence scan.To comprehensively evaluate the correlation between various imaging indexes and T2DM,and summarize the main characteristics of pancreatic changes in T2DM.Methods:50 T2DM patients and 50 non-diabetic volunteers were recruited for upper abdominal MRI.The ratio of pancreatic volume to body surface area,pancreatic fat content and the morphological grading of pancreatic margin were measured.Results:The ratio of pancreatic volume to body surface area in T2DM group was(36.38±9.62)cm^(3)/m^(2),which was statistically lower than that in the control group of(46.94±8.67)cm^(3)/m^(2)(P<0.001).The pancreatic fat content in T2DM group was(6.17±2.89)%,which was statistically higher than that in the control group of(3.64±3.47)%(P<0.05).The morphological grading of pancreatic margin in T2DM group was(1.80±1.03),which was statistically higher than that in the control group of(1.26±0.99)(P=0.440).Conclusions:T2DM patients have an increase in pancreatic fat content and a decrease in pancreatic volume.MRI multi-sequence scan can provide accurate evaluation for the changes of pancreatic fat content and volume.

关 键 词：2型糖尿病 磁共振成像 胰腺 体积 脂肪 

分 类 号：R587.1[医药卫生—内分泌] R445.2[医药卫生—内科学]