内镜下黏膜剥离术治疗食管早癌的临床研究  

Clinical study of endoscopic mucosal dissection in the treatment of esophageal early cancer

作　　者：朱琳[1] 张毅 李阳子 李玉玲 Zhu Lin;Zhang Yi;Li Yangzi;Li Yuling(Endoscopy Center,The First Affiliated Hospital of Nanyang Medical College,Nanyang 473000,China)

机构地区：[1]南阳医学高等专科学校第一附属医院内镜中心,南阳473000

出　　处：《现代仪器与医疗》2024年第3期82-85,共4页Modern Instruments & Medical Treatment

基　　金：2021年度南阳市科技攻关项目(KJGG153)。

摘　　要：目的评价内镜下黏膜剥离术治疗食管早癌的疗效和安全性。方法选取2021年1月—2022年12月我院收治的60例食管早癌患者为研究对象,按照手术方式不同分为两组,每组30例,分别实施常规外科手术与内镜下黏膜剥离术。比较两组各项临床指标、病灶剥离与切除情况、术后并发症发生情况及生活质量水平。结果研究组的出院时间、手术时间、术后进食时间短于对照组(P<0.05)。研究组的出血量少于对照组(P<0.05)。研究组的病灶剥离与切除效果优于对照组(P<0.05)。研究组的术后并发症总发生率低于对照组(P<0.05)。研究组的生活质量水平高于对照组(P<0.05)。结论内镜下黏膜剥离术治疗食管早癌,其可以有效优化患者各项临床指标与病灶剥离与切除效果,并大幅度降低并发症的发生率,治疗安全性较高。Objective Evaluation of the efficacy and safety of endoscopic mucosal dissection in the treatment of early esophageal cancer.Methods 60 patients with early esophageal cancer admitted to our hospital from January 2021 to December 2022 were selected as the research objects and divided into two groups according to different operation methods,with 30 cases in each group,regular surgery and endoscopic submucosal dissection were performed respectively.The clinical indicators,lesion dissection and resection,postoperative complications and quality of life were compared between the two groups.Results The discharge time,operation time and postoperative feeding time of the study group were shorter than those of the control group(P<0.05).And the amount of bleeding of the study group was less than that of the control group(P<0.05).The effect of lesion stripping and resection in the study group was better than that in the control group(P<0.05).The incidence of postoperative complications in the study group was lower than that in the control group(P<0.05).The quality of life in the study group was higher than that in the control group(P<0.05).Conclusion Endoscopic submucosal dissection in the treatment of early esophageal cancer can effectively optimize the clinical indicators and the effect of lesion dissection and resection,and greatly reduce the incidence of complications and improve the safety of treatment.

关 键 词：内镜下黏膜剥离术 食管早癌 病灶剥离 术后并发症 生活质量 

分 类 号：TH77[机械工程—仪器科学与技术] R735[机械工程—精密仪器及机械]