Understanding the etiology of mental health problems in postrehabilitation COVID-19 patients:Insights and strategies for effective intervention  

作　　者：Hai-Sheng Hu Bao-Qing Sun 

机构地区：[1]Guangzhou Respiratory Health Research Institute,The First Affiliated Hospital of Guangzhou Medical University,Guangzhou 510120,Guangdong Province,China [2]Department of Clinical Laboratory,The First Affiliated Hospital of Guangzhou Medical University,Guangzhou 510120,Guangdong Province,China

出　　处：《World Journal of Clinical Cases》2024年第23期5308-5312,共5页世界临床病例杂志

基　　金：Guangzhou Laboratory Emergency Research Project,No.EKPG21-302.

摘　　要：In this editorial,we comment on an article by Alhammad et al that was published in a recent issue of the World Journal of Clinical Cases(Manuscript No.:91134).We specifically focus on the mental health problems caused by coronavirus disease 2019(COVID-19),their mechanisms,and targeted rehabilitation strategies.Severe acute respiratory syndrome coronavirus 2,via its spike protein,binds to angiotensin-converting enzyme 2 and other receptors prior to infiltrating diverse cells within the central nervous system,including endothelial cells,neurons,astrocytes,and oligodendrocytes,thereby contributing to the development of mental illnesses.Epidemiological data from 2020 underscored the global upsurge in major depressive and anxiety disorders by 27.6%and 25.6%,respectively,during the pandemic.The commented research show that 30%of post-intensive care unit discharge patients with COVID-19 in the Arabic region exhibited Hospital Anxiety and Depression Scale scores that were indicative of anxiety and depression.While acknowledging psychosocial factors,such as grief and loss,it is crucial to recognize the potential neurological impact of the virus through various mechanisms.Accordingly,interventions that encompass dietary measures,health supplements,and traditional Chinese medicine with neuroprotective properties are necessary.This editorial underscores the urgency to implement comprehensive rehabilitation approaches to address the intricate interplay between COVID-19 and mental well-being.

关 键 词：COVID-19 Mental health Rehabilitation therapy Chronic COVID-19 syndrome Social medicine 

分 类 号：R472.3[医药卫生—护理学]