Influence of perinatal factors on full-term low-birth-weight infants and construction of a predictive model  

作　　者：Liang Xu Xue-Juan Sheng Lian-Ping Gu Zu-Ming Yang Zong-Tai Feng Dan-Feng Gu Li Gao 

机构地区：[1]Department of Neonatology,Suzhou Ninth People's Hospital,Suzhou 215200,Jiangsu Province,China [2]Department of Obstetrics,Suzhou Ninth People's Hospital,Suzhou 215200,Jiangsu Province,China [3]Department of Neonatology,Suzhou Municipal Hospital,Suzhou 215008,Jiangsu Province,China

出　　处：《World Journal of Clinical Cases》2024年第26期5901-5907,共7页世界临床病例杂志

摘　　要：BACKGROUND Being too light at birth can increase the risk of various diseases during infancy.AIM To explore the effect of perinatal factors on term low-birth-weight(LBW)infants and build a predictive model.This model aims to guide the clinical management of pregnant women’s healthcare during pregnancy and support the healthy growth of newborns.METHODS A retrospective analysis was conducted on data from 1794 single full-term pregnant women who gave birth.Newborns were grouped based on birth weight:Those with birth weight<2.5 kg were classified as the low-weight group,and those with birth weight between 2.5 kg and 4 kg were included in the normal group.Multiple logistic regression analysis was used to identify the factors influencing the occurrence of full-term LBW.A risk prediction model was established based on the analysis results.The effectiveness of the model was analyzed using the Hosmer–Leme show test and receiver operating characteristic(ROC)curve to verify the accuracy of the predictions.RESULTS Among the 1794 pregnant women,there were 62 cases of neonatal weight<2.5 kg,resulting in an LBW incidence rate of 3.46%.The factors influencing full-term LBW included low maternal education level[odds ratio(OR)=1.416],fewer prenatal examinations(OR=2.907),insufficient weight gain during pregnancy(OR=3.695),irregular calcium supplementation during pregnancy(OR=1.756),and pregnancy hypertension syndrome(OR=2.192).The prediction model equation was obtained as follows:Logit(P)=0.348×maternal education level+1.067×number of prenatal examinations+1.307×insufficient weight gain during pregnancy+0.563×irregular calcium supplementation during pregnancy+0.785×pregnancy hypertension syndrome−29.164.The area under the ROC curve for this model was 0.853,with a sensitivity of 0.852 and a specificity of 0.821.The Hosmer–Leme show test yieldedχ^(2)=2.185,P=0.449,indicating a good fit.The overall accuracy of the clinical validation model was 81.67%.CONCLUSION The occurrence of full-term LBW is related to maternal educ

关 键 词：Pregnant women Perinatal care Low-birth-weight infants Influencing factors Prediction model 

分 类 号：R722[医药卫生—儿科]