Periorbital purpura can be the only initial symptom of primary light chain amyloidosis:A case report  

作　　者：Xiu-Feng Wang Ting Li Man Yang Yan Huang 

机构地区：[1]Department of Hematology,The First Affiliated Hospital of Xinxiang Medical University,Xinxiang 453100,Henan Province,China [2]Department of Blood Purification,The First Affiliated Hospital of Xinxiang Medical University,Xinxiang 453100,Henan Province,China

出　　处：《World Journal of Clinical Cases》2024年第26期5946-5951,共6页世界临床病例杂志

基　　金：Supported by the Henan Province Medical Science and Technology Research Plan Joint Construction Project,No.LHGJ20210533;Xinxiang Science and Technology Research Project,No.GG2020029.

摘　　要：BACKGROUND Primary light chain amyloidosis is a rare and complex disease with complex clinical features and is highly susceptible to misdiagnosis and underdiagnosis in the early stages.CASE SUMMARY We report a case of a 47-year-old female patient whose only initial symptom was periorbital purpura,which was not taken seriously enough.As the disease progressed,pleural effusion gradually appeared,and after systematic diagnosis and treatment,she was diagnosed with“primary light chain amyloidosis”.She achieved rapid hematological remission after treatment with a daratumumab+bortezomib+cyclophosphamide+dexamethasone regimen.CONCLUSION Periorbital purpura can be the only initial symptom of primary light chain amyloidosis;we should pay attention to the cases where the initial clinical symptoms are only periorbital purpura.

关 键 词：Primary light chain amyloidosis Periorbital purpura Initial symptom Literature review Case report 

分 类 号：R554.6[医药卫生—血液循环系统疾病]