小花姜花根茎的化学成分研究  

Studies on the Constituents from the Rhizomes of Hedychium Sinoaureum

作　　者：罗兴礼 彭伟[1] 刘波[1] 郑丽[1] 殷发胜 陈业高[1] LUO Xingli;PENG Wei;LIU Bo;ZHENG Li;YIN Fasheng;CHEN Yegao(School of Chemistry and Chemical Engineering,Yunnan Normal University,Kunming 650500,China)

机构地区：[1]云南师范大学化学化工学院,云南昆明650500

出　　处：《海南师范大学学报（自然科学版）》2024年第2期189-194,共6页Journal of Hainan Normal University（Natural Science）

基　　金：云南省高校药用活性分子结构多样性研究重点实验室资助项目。

摘　　要：小花姜花(Hedychium sinoaureum Stapf.)根茎部分风干粉碎后用甲醇浸提。浸提物溶于水后用乙酸乙酯萃取,乙酸乙酯萃取部分综合运用多种现代分离手段,包括正反相硅胶柱色谱、MCI、Sephadex LH-20层析和半制备高效液相层析,分离得到8个化合物,结构鉴定为3个黄酮类,2个倍半萜类,1个二芳基庚烷类和2个芳香类化合物,分别为:pinocembrin(1)、3,5,7,4'-四甲氧基黄酮(2)、5-羟基-3,7,4'-三甲氧基黄酮(3)、3,7,11-trimethyldodeca-1,6,10-triene-3,9-diol(4)、3,7,11-trimethyldodeca-l,6,9-triene-3,11-diol(5)、letestuianin B(6)、5,6-dehydrokawain(7)、vanillin(8)。化合物1,2和44~7为第一次从小花姜花中分离得到。The rhizomes of Hedychium sinoaureum were extracted with methanol after air drying and crushing.The extract was dissolved with water and then extracted with ethyl acetate,which was separated by silica gel column chromatography,RP-18,Sephadex LH-20chromatography and HPLC.Various modern spectroscopic techniques were applied for the structural identification of the isolated compounds,and eight compounds were obtained,including three flavonoids,two sesquiterpenes,one diaryl heptanes,two simple aromatics.Their structures were elucidated as pinocembrin(1),3,5,7,4'-tetramethoxyflavone(2),kaempferol-3,4',7-O-trimethylether(3),3,7,11-trimethyldodeca-1,6,10-triene-3,9-diol(4),3,7,11-trimethyldodeca-1,6,9-triene-3,11-diol(5),letestuianin B(6),5,6-dehydrokawain(7)and vanillin(8)respectively.Compounds 1,2 and 4-7 were isolated from the plant for the first time.

关 键 词：小花姜花 化学成分 黄酮类化合物 倍半萜类化合物 

分 类 号：R284.1[医药卫生—中药学]