Bridging the gap in cardiac mass diagnosis:Advanced imaging,genetic associations,and biomarkers  

作　　者：Yi-Hao Loh Xu-Lin Hong 

机构地区：[1]School of Medicine,School of Medicine,Zhejiang University,China,Hangzhou 310000,Zhejiang Province,China [2]Department of Cardiology,Sir Run Run Shaw Hospital,College of Medicine,Zhejiang University,Hangzhou 310000,Zhejiang Province,China

出　　处：《World Journal of Clinical Cases》2024年第22期4859-4864,共6页世界临床病例杂志

摘　　要：In this editorial we comment on the article by Huffaker et al published in a recent issue of the World Journal of Clinical Cases.We focus on cardiac tumors linked to genetic syndromes and the differential diagnosis of cardiac masses.As cardiomyocytes lack the ability to actively divide,primary cardiac tumors are extremely rare across all ethnicities and age groups.Once they occur,these tumors are often associated with genetic mutations and,occasionally,genetic syndromes.This underscores the importance of considering genetic mutations and syndromes when encountering these cases.The more common growths in the heart are thrombi and vegetations,which can mimic tumors,further making the differential diagnosis challenging.Among the imaging techniques,contrast-enhanced cardiac magnetic resonance imaging has the highest sensitivity for differential diagnosis.To aid in the differential diagnosis of cardiac masses,especially thrombi,appropriate utilization of biomarkers(i.e.D-dimer level)may provide pivotal clinical implications.Employing a multidisciplinary approach that integrates personal history,epidemiological insights,imaging findings,genetic markers,and biomarkers is therefore critical in the diagnostic process of cardiac masses.

关 键 词：Cardiac masses Genetic syndromes THROMBI IMAGING D-DIMER 

分 类 号：R541[医药卫生—心血管疾病]