Botulinum toxin type A injection combined with biofeedback in the treatment of spastic pelvic floor syndrome  

作　　者：Fei-Fei Sun Yong-Qiang Chen Zong-Lin Jiang Lin Ma 

机构地区：[1]Department of Anorectal Surgery,The Eighth People's Hospital of Qingdao,Qingdao 266000,Shandong Province,China

出　　处：《World Journal of Clinical Cases》2024年第22期4905-4912,共8页世界临床病例杂志

摘　　要：BACKGROUND Spastic pelvic floor syndrome(SPFS)is a refractory pelvic floor disease characterized by abnormal(uncoordinated)contractions of the external anal sphincter and puborectalis muscle during defecation,resulting in rectal emptation and obstructive constipation.The clinical manifestations of SPFS are mainly characterized by difficult defecation,often accompanied by a sense of anal blockage and drooping.Manual defecation is usually needed during defecation.From physical examination,it is commonly observed that the patient's anal muscle tension is high,and it is difficult or even impossible to enter with his fingers.AIM To investigate the characteristics of anorectal pressure and botulinum toxin A injection combined with biofeedback in treating pelvic floor muscle spasm syndrome.METHODS Retrospective analysis of 50 patients diagnosed with pelvic floor spasm syndrome.All patients underwent pelvic floor surface electromyography assessment,anorectal dynamics examination,botulinum toxin type A injection 100 U intramuscular injection,and two cycles of biofeedback therapy.RESULTS After the botulinum toxin A injection combined with two cycles of biofeedback therapy,the patient's postoperative resting and systolic blood pressure were significantly lower than before surgery(P<0.05).Moreover,the electromyography index of the patients in the resting stage and post-resting stages was significantly lower than before surgery(P<0.05).CONCLUSION Botulinum toxin A injection combined with biofeedback can significantly reduce pelvic floor muscle tension in treating pelvic floor muscle spasm syndrome.Anorectal manometry is an effective method to evaluate the efficacy of treatment objectively.However,randomized controlled trials are needed.

关 键 词：Spastic pelvic floor syndrome Botulinum toxin A BIOFEEDBACK Anorectal pressure measurement Agachan constipation score 

分 类 号：R68[医药卫生—骨科学]