Effectiveness of onsite and online education in enhancing knowledge and use of human immunodeficiency virus pre-and postexposure prophylaxis  

作　　者：Ying Shao Mei Zhang Li-Jun Sun Hong-Wei Zhang An Liu Xi Wang Ruo-Lei Xin Jian-Wei Li Jiang-Zhu Ye Yue Gao Zhang-Li Wang Zai-Cun Li Tong Zhang 

机构地区：[1]Clinic of Center for Infection,Beijing Youan Hospital,Capital Medical University,Beijing 100069,China [2]Department of Infectious Diseases and Medical Immunology,Beijing Youan Hospital,Capital Medical University,Beijing 100069,China [3]Chinese Association of STD and AIDS Prevention and Control,Beijing 100050,China [4]Institute of STD/AIDS Prevention and Control,Beijing Center for Disease Prevention and Control,Beijing 100013,China

出　　处：《World Journal of Clinical Cases》2024年第22期5042-5050,共9页世界临床病例杂志

基　　金：This study received ethical approval from the ethics committee of Beijing Youan Hospital,Capital Medical University[No.(2021)078];the research was implemented in strict conformity with the guidelines outlined in the Declaration of Helsinki.

摘　　要：BACKGROUND Enhancing awareness and use of pre-exposure prophylaxis(PrEP)and postexposure prophylaxis(PEP)is vital to curb human immunodeficiency virus(HIV)spread.High-risk behaviors prevalent among sexually transmitted infection clinic outpatients underscore the need for increased PrEP/PEP education in this group.AIM To investigate the effects of both onsite and online health education on the knowledge of,and willingness to use,PrEP and PEP among individuals receiving PEP services.METHODS Participants were drawn from a cohort study on PEP service intervention at an STD/AIDS outpatient clinic in designated HIV/AIDS hospitals in Beijing,conducted from January 1 to June 30,2022.Health education was provided both onsite and online during follow-up.Surveys assessing knowledge of,and willingness to use,PrEP/PEP were administered at baseline and again at 24 wk post-intervention.RESULTS A total of 112 participants were enrolled in the study;105 completed the follow-up at week 24.The percentage of participants with adequate knowledge of,and willingness to use,PrEP significantly increased from 65.2%and 69.6%at baseline to 83.8%and 82.9%at the end of the intervention(both P<0.05).Similarly,those with adequate knowledge of,and willingness to use,PEP increased from 74.1%and 77.7%at baseline to 92.4%and 89.5%at week 24(P<0.05).Being between 31 years and 40 years of age,having a postgraduate degree or higher,and reporting a monthly expenditure of RMB 5000 or more were found to be significantly associated with knowledge of PrEP and PEP(both P<0.05).CONCLUSION The findings show that both onsite and online health education significantly improved the knowledge of,and increased willingness to use,PrEP and PEP in individuals utilizing PEP services.

关 键 词：Human immunodeficiency virus Pre-exposure prophylaxis Post-exposure prophylaxis Health education INTERVENTION 

分 类 号：R392[医药卫生—免疫学]