Diabetes remission and nonalcoholic fatty pancreas disease  

作　　者：Wen-Jun Wu 

机构地区：[1]Department of Endocrinology,Jinshan Branch of Shanghai Sixth People’s Hospital,Shanghai 201500,China

出　　处：《World Journal of Diabetes》2024年第7期1390-1393,共4页世界糖尿病杂志（英文版）（电子版）

摘　　要：This editorial focuses on the relationship between nonalcoholic fatty pancreas disease(NAFPD)and the development and remission of type 2 diabetes(T2D).NAFPD is characterized by intrapancreatic fatty deposition associated with obesity and not associated with alcohol abuse,viral infections,and other factors.Ectopic fat deposition in the pancreas is associated with the development of T2D,and the underlying mechanism is lipotoxicβ-cell dysfunction.However,the results on the relationship between intrapancreatic fat deposition(IPFD)andβ-cell function are conflicting.Regardless of the therapeutic approach,weight loss improves IPFD,glycemia,andβ-cell function.Pancreatic imaging is valuable for clinically monitoring and evaluating the management of T2D.

关 键 词：Diabetes remission Type 2 diabetes Pancreatic fat content βcell function Weight loss 

分 类 号：R587.1[医药卫生—内分泌] R576[医药卫生—内科学]