Management of gestational diabetes mellitus via nutritional interventions:The relevance of gastric emptying  

作　　者：Wei-Kun Huang Ryan J Jalleh Christopher K Rayner Tong-Zhi Wu 

机构地区：[1]Adelaide Medical School and Centre of Research Excellence in Translating Nutritional Science to Good Health,The University of Adelaide,Adelaide 5000,Australia [2]Adelaide Medical School and Centre of Research Excellence in Translating Nutritional Science to Good Health,The University of Adelaide and Department of Gastroenterology and Hepatology,Royal Adelaide Hospital,Adelaide 5000,Australia

出　　处：《World Journal of Diabetes》2024年第7期1394-1397,共4页世界糖尿病杂志（英文版）（电子版）

摘　　要：Gestational diabetes mellitus(GDM)represents one of the most common medical complications of pregnancy and is important to the well-being of both mothers and offspring in the short and long term.Lifestyle intervention remains the mainstay for the management of GDM.The efficacy of nutritional approaches(e.g.calorie restriction and small frequent meals)to improving the maternal-neonatal outcomes of GDM was attested to by Chinese population data,discussed in two articles in recent issues of this journal.However,a specific focus on the relevance of postprandial glycaemic control was lacking.Postprandial rather than fasting hyperglycaemia often represents the predominant manifestation of disordered glucose homeostasis in Chinese women with GDM.There is now increasing appreciation that the rate of gastric emptying,which controls the delivery of nutrients for digestion and absorption in the small intestine,is a key determinant of postprandial glycaemia in both health,type 1 and 2 diabetes.It remains to be established whether gastric emptying is abnormally rapid in GDM,particularly among Chinese women,thus contributing to a predisposition to postprandial hyperglycaemia,and if so,how this influences the therapeutic response to nutritional interventions.It is essential that we understand the role of gastric emptying in the regulation of postprandial glycaemia during pregnancy and the potential for its modulation by nutritional strategies in order to improve postprandial glycaemic control in GDM.

关 键 词：Gastric emptying Postprandial glycaemia DIET Nutritional interventions Gestational diabetes mellitus 

分 类 号：R714.256[医药卫生—妇产科学]