硫化氢在延缓脑老化作用中的研究进展  

Progress of hydrogen sulfide in delaying brain aging

作　　者：孙凤起 罗孝廷 刘宏[1] 宋运佳 SUN Fengqi;LUO Xiaoting;LIU Hong;SONG Yunjia(School of Basic Medicine Sciences,Heilongjiang University of Chinese Medicine,Harbin 150040,China)

机构地区：[1]黑龙江中医药大学基础医学院,黑龙江哈尔滨150040

出　　处：《基础医学与临床》2024年第8期1185-1188,共4页Basic and Clinical Medicine

基　　金：黑龙江省自然科学基金优秀青年项目(YQ2022H020)。

摘　　要：脑老化与认知功能减退、神经退行性疾病和血管性痴呆密切相关。硫化氢(H_(2)S)能通过调节蛋白质稳态、抗氧化应激、抑制炎性反应、减少脑细胞凋亡和改善微循环延缓脑老化。Brain aging is closely related to cognitive decline,neurodegenerative diseases,and vascular dementia.Hydrogen sulfide(H_(2)S)can delay brain aging by regulating protein homeostasis,anti-oxidative stress,inhibiting inflammation,reducing brain cell apoptosis and improving microcirculation.

关 键 词：脑老化 硫化氢 硫巯基化 

分 类 号：R338.2[医药卫生—人体生理学]