膜分离技术在中药绿色制造中的应用与展望  

Application and prospect of membrane separation technology in green manufacturing of traditional Chinese medicine

作　　者：董治国 周容 何金凤 刘文龙[1] 陈雨晴 王虎传 李传润 颜海洋[1,2,3] DONG Zhiguo;ZHOU Rong;HE Jinfeng;LIU Wenlong;CHEN Yuqing;WANG Huchuan;LI Chuanrun;YAN Haiyang(School of Pharmacy,Anhui University of Chinese Medicine,Hefei 230012,China;Pharmaceutical Engineering Technology Research Center,Anhui University of Chinese Medicine,Hefei 230012,China;Anhui Province Key Laboratory of Pharmaceutical Preparation Technology and Application,Hefei 230012,China)

机构地区：[1]安徽中医药大学药学院,安徽合肥230012 [2]安徽中医药大学制药工程技术研究中心,安徽合肥230012 [3]药物制剂技术与应用安徽省重点实验室,安徽合肥230012

出　　处：《中草药》2024年第12期4225-4234,共10页Chinese Traditional and Herbal Drugs

基　　金：国家重点研发计划项目(2022YFB3805103);国家重点研发计划项目(2022YFB3805102);国家自然科学基金资助项目(22008226);安徽省高校优秀青年科研项目(2022AH030063);安徽中医药大学人才支持计划项目重大项目(2022rcZD005);烟草化学安徽省重点实验室开放课题(2022302)。

摘　　要：膜分离技术由于其独特的分离机制,能够实现中药制药的高效分离与纯化,从而实现中药绿色制造,推动中药行业绿色、高质量发展。通过对近年来微滤、超滤、纳滤、膜蒸馏、集成膜技术及其他膜分离技术在中药绿色制造中的应用进行综述,并探讨膜分离技术在中药制药中的应用前景,可为中药绿色制造提供新思路,推动膜分离技术在中药制药过程中的新应用和新发展。Membrane separation technology,due to its unique separation mechanism,is capable of realizing efficient separation and purification of traditional Chinese medicine(TCM)pharmaceuticals,thus realizing the green manufacturing of TCM and promoting the green and high-quality development of the TCM industry.In this paper,we summarized the progress of the application of microfiltration,ultrafiltration,nanofiltration,membrane distillation,integrated membrane technology,and the other membrane separation technology in the green manufacturing of TCM in recent years,and discussed the prospect of the application of membrane separation technology in TCM pharmaceuticals.The above insights will provide new ideas for the green manufacturing of TCM,and promote the new application and development of membrane separation technology in the pharmaceutical process of TCM.

关 键 词：膜分离 中药 绿色制造 微滤 超滤 纳滤 膜蒸馏 集成膜技术 反渗透 电渗析 

分 类 号：R283[医药卫生—中药学]