恶性肿瘤复合病机理论指导下温滋解毒法的构建  

Construction of Detoxication Method of Warming and Nourishing under the Guidance of Compound Pathogenesis Theory of Malignant Tumor

作　　者：袁伟琛 周红光[1,2,3] 庄育培 周洪立 吴勉华 YUAN Weichen;ZHOU Hongguang;ZHUANG Yupei;ZHOU Hongli;WU Mianhua(The First School of Clinical Medicine,Nanjing University of Chinese Medicine,Nanjing 210023,China;Jiangsu Collaborative Innovation Centre for Traditional Chinese Medicine Prevention and Treatment of Tumours,Nanjing 210023,China;The Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210029,China;School of Pharmacy,Nanjing University of Chinese Medicine,Nanjing 210023,China)

机构地区：[1]南京中医药大学第一临床医学院,江苏南京210023 [2]江苏省中医药防治肿瘤协同创新中心,江苏南京210023 [3]南京中医药大学附属医院,江苏南京210029 [4]南京中医药大学药学院,江苏南京210023

出　　处：《南京中医药大学学报》2024年第6期543-549,共7页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：国家自然科学基金面上项目(81973737);江苏省中医药科技发展项目重点项目(ZD202301);第二届全国名中医工作室建设项目(国中医药人教函〔2022〕245号);吴勉华全国名老中医药专家传承工作室建设项目(国中医药人教函〔2022〕75号);吴勉华江苏省名老中医药专家传承工作室建设项目(苏中医科教〔2021〕7号)。

摘　　要：基于恶性肿瘤的复合病机,将正邪、阴阳和中气等理论与癌毒理论相整合,指出正虚邪盛为肿瘤的发病基础。阴阳俱损、气机郁滞、癌毒深伏为肿瘤的病机特点。认为阴阳俱损多起于脾肾,气机郁滞首先责之于脾胃,癌毒深伏常兼夹多种邪气。基于此提出以温滋解毒法为恶性肿瘤的基本治法。温滋解毒法是温法、滋法、解毒法三法并用或次第应用,共同发挥温滋并用,调和阴阳;行气解郁,调畅情志;消癌解毒,破兼夹之邪的功效。Based on the compound pathogenesis theory of malignant tumor,this article combines the theories of positive-evil,yin-yang,and central qi theories with the theory of cancer toxin,pointing out that the deficiency of positive and excess of evil are the basis for the onset of tumors.The pathogenesis characteristics of tumors are the loss of both yin and yang,stagnation of qi,and cancer toxin deeply lurking.The paper believes that the loss of both yin and yang often originates from the spleen and kidney,stagnation of qi is first blamed on the spleen and stomach,and cancer toxin deeply lurking often accompanies multiple evil qi.Based on this,the detoxication method of warming and nourishing is proposed to treat malignant tumors.It is the combination or sequential application of the three methods of warming,nourishing,and detoxification,which play the role of warming and nourishing together,harmonizing yin and yang;promoting the circulation of qi,relieving depression,and regulating emotions;eliminating cancer and toxin,and breaking the combined evil.

关 键 词：恶性肿瘤 复合病机 正虚邪盛 阴阳俱损 气机郁滞 癌毒深伏 温滋解毒法 

分 类 号：R273[医药卫生—中西医结合]