饮食干预治疗婴儿食物蛋白诱导的过敏性直肠结肠炎临床研究  

A clinical study of dietary intervention in the treatment of food protein-induced allergic proctocolitis in infants

作　　者：尹延娥[1] 李雪 陈坤琦 张爱梅[1] YIN Yane;LI Xue;CHEN Kunqi;ZHANG Aimei(Department of Neonatology,Weifang People's Hospital,Weifang 261041,China)

机构地区：[1]潍坊市人民医院新生儿科,山东潍坊261041

出　　处：《潍坊医学院学报》2024年第3期198-201,共4页Acta Academiae Medicinae Weifang

基　　金：潍坊市卫生健康委员会项目(项目编号:WFWSJK-2020-266)。

摘　　要：目的 探讨以便血为主要症状的食物蛋白诱导的过敏性直肠结肠炎(FPIAP)患儿的治疗方法,评估各组患儿的生长发育及过敏症状改善情况。方法 选取2019年1月~2021年7月我院诊断的出生0~3个月食物蛋白诱导的FPIAP婴儿为研究对象,随机分为对照组和观察组。对照组采取母乳喂养,母亲回避特殊食物蛋白饮食,观察组采取氨基酸配方奶粉喂养,记录、分析患儿治疗0个月、3个月、6个月的头围、身长及体重,便血、腹泻等临床症状改善的情况,并记录分析两组患儿经饮食干预后便血消失时间及腹泻消失时间。结果 两组患儿共93例,对照组41例,观察组52例。治疗0个月、3个月、6个月两组患儿生长发育情况头围、身长、体重,差异无统计学意义(P>0.05)。观察组在便血消失时间、腹泻消失短于对照组,差异有统计学意义(P<0.05)。结论 两种饮食干预方法均能够治疗患儿的便血等临床症状,改善患儿的生长发育,但氨基酸配方奶粉喂养在缓解便血等症状方面时间更短。Objective To investigate the treatment of food protein-induced allergic proctocolitis(FPIAP)and atopic dermatitis in children with bloody stool as the main symptom,and to evaluate the growth and development of children and the improvement of allergic symptoms in each group.Methods Infants with O~3 months of food protein-in-duced allergic proctitis diagnosed in our hospital from January 2019 to July 2021 were selected as the research objects and divided into two groups,the control group and the observation group.The control group was breasfed,and the moth-ers avoided special food protein diets,while the observation group was fed with amino acid formula milk powder.The head circumference,length and weight of the children,the improvement of clinical symptoms such as hematochezia and diarrhea at O month,3 months and 6 months after treatment were recorded and analyzed,and the disappearance time of hematochezia and diarrhea after dietary intervention in the two groups were recorded and analyzed.Results There were 93 children in the two groups,41 in the control group and 52 in the observation group.There was no significant difference in the growth and development of head circumference,body length and weight between the two groups at O month,3 months and 6 months after treatment(P>0.05).The disappearance time of bloody stool and diarrhea in the observation group was shorter than that in the control group,and the dfference was statistically significant(P<0.05).Conclusion Two dietary interventions can treat clinical symptoms such as hematochezia in children and improve their growth and development,but amino acid formula milk powder feeding has a shorter time in relieving hematochezia and other symptoms.

关 键 词：牛奶蛋白 饮食干预 氨基酸配方 

分 类 号：R725.7[医药卫生—儿科]