从“肠道微生态”角度初探夏桂成教授“心(脑)肾-肝脾-子宫轴”的理论创新及用药思考  

Exploring Professor Xia Guicheng's Theoretical Innovation and Medication Thinking on the“Heart(Brain-Kidney)-Liver Spleen-Uterus Axis”from the Perspective of“Intestinal Microecology”

作　　者：陈雯玥 马桦 任青玲[1] CHEN Wen-yue;MA Hua;REN Qing-ling(Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing Jiangsu 210029,China)

机构地区：[1]南京中医药大学附属医院,江苏南京210029

出　　处：《时珍国医国药》2024年第5期1226-1228,共3页Lishizhen Medicine and Materia Medica Research

基　　金：国家自然科学基金(82104904);江苏省中医院院级课题(Y21001);江苏省中医妇产生殖临床医学创新中心(苏中医科教[2021]6号);第四批江苏省名老中医药专家传承工作室(苏中医科教[2021]7号)。

摘　　要：国医大师夏桂成教授(以下尊称“夏老”)在临床反复实践中对“心-肾-子宫轴”产生了新的认识,肝脾为枢纽,同为生化之源,协助心肾相交。基于“肠道微生态”的现代医学内涵,阐述其在“心(脑)肾-肝脾-子宫轴”理论中的加入“肝脾”二脏的分子基础,进而证实“肠道菌-卵巢轴”平衡是其功能正常的重要因素。临证用药以调和肝脾四法为基础,最终达到心肾同治、肝脾同调的境地,并贯穿于“调周法”的全过程。Professor Xia Guicheng,a master of traditional Chinese medicine(respected as“Xia Lao”bellow),developed a new understanding of the“hear-kidney-uterus axis”through clinical practice.The liver and spleen are the hubs,the origination of body,and assist in the intercourse between heart and kidney.Based on the modern medical connotation of“gut microbiota”,this article elaborates on the molecular basis of adding“liver and spleen”to the“heart(brain-kidney)-liver spleen-uterus axis”theory,and further confirms that the balance of“gut-ovarian axis”is an important factor in its normal function.Clinical medication is based on the four methods of harmonizing the liver and spleen,ultimately achieving the state of simultaneous treatment of the heart and kidney,liver and spleen,and through the entire process of the“regulating the week method”.

关 键 词：“肠道微生态” “心(脑)-肝脾-肾-子宫轴” “肠道菌-卵巢轴” 夏桂成 心肾同治 肝脾同调 

分 类 号：R249.2[医药卫生—中医临床基础] R249.7[医药卫生—中医学]