一例山羊金黄色葡萄球菌和伪结核棒状杆菌混合感染的调查分析  

Investigation and Analysis of Mixed Infection of Staphylococcus Aureus and Corynebacterium Pseudotuberculosis in a Case of Goats

作　　者：霍秀龙 周沛[2,3] 贺会利 黄善 兰肖萍 冯世文 胡帅[2,3] 吴翠兰 钟舒红[2,3] 彭昊 李军 HUO Xiulong;ZHOU Pei;HE Huili;HUANG Shan;LAN Xiaoping;FENG Shiwen;HU Shuai;WU Cuilan;ZHONG Suhong;PENG Hao;LI Jun(Animal Disease Prevention and Control Center of Pingguo City,Baise,Guangxi 531400,China;Guangxi Key Laboratory of Veterinary Biotechnology,Guangxi Veterinary Research Institute,Nanning,Guangxi 530001,China;China(Guangxi)-ASEAN Key Laboratory of Cross-border Animal Disease Control,Ministry of Agriculture and Rural Affairs,Nanning,Guangxi 530001,China)

机构地区：[1]平果市动物疫病预防控制中心,广西百色531400 [2]广西兽医研究所广西兽医生物技术重点实验室,广西南宁530001 [3]农业农村部中国(广西)—东盟跨境动物疫病防控重点实验室,广西南宁530001

出　　处：《广西农学报》2024年第2期20-25,33,共7页Journal of Guangxi Agriculture

基　　金：广西重点研发计划(桂科AB23026082);广西畜牧产业科技先锋队专项(桂农科盟202309-01-2)。

摘　　要：旨在调查分析广西平果市部分母羊全身各部位出现皮下脓包、影响采食和运动,导致母羊偏瘦的原因。采用细菌分离培养、分子生物学及寄生虫形态学方法对脓液及其粪便进行检测。分离脓液中的金黄色葡萄球菌和伪结核棒状杆菌,检验粪便中的球虫虫卵。药敏试验结果显示,混合菌对青霉素、阿莫西林、环丙沙星、阿米卡星、头孢他啶、多西环素、头孢喹肟、头孢噻呋、泰地罗新、加米霉素、长效阿莫西林和氟苯尼考高度敏感,对卡那霉素中度敏感,对头孢氨苄、链霉素、壮观霉素、恩诺沙星、新霉素、磷霉素、马波沙星、林可霉素及阿奇霉素耐药。通过实验室检测,确诊本次病例为金黄色葡萄球菌、伪结核棒状杆菌和球虫病混合感染。根据以上检测结果,指导养殖场科学合理地制订治疗方案,从而控制病情。The aim of this paper was to investigate and analyze the causes of subcutaneous abscesses in various parts of bodies of some ewes in Pingguo city of Guangxi,which affected their feeding and exercise and led to leanness.The methods of bacterial isolation and culture,molecular biology and parasite morphology were used to detect pus and stool.Staphylococcus aureus and Corynebacterium pseudotuberculosis were isolated from the pus,and coccidium eggs were found in the feces.The results of the drug sensitivity test showed that the mixed bacteria were highly sensitive to penicillin,amoxicillin,ciprofloxacin,amikacin,ceftazidime,doxycycline,ceftioxime,ceftiofurosin,gamamycin,amoxicillin,flufenicol,and moderately sensitive to kanamycin.There were resistant to cephalexin,streptomycin,pomomycin,enrofloxacin,neomycin,fosfomycin,marbofloxacin,lincomycin and azithromycin.The case was confirmed as a mixed infection of Staphylococcus aureus,Corynebacterium pseudotuberculosis,and coccidiosis by laboratory testing.Based on the above test results,the farms can be guided to develop scientific and reasonable treatment plan in order to control the disease.

关 键 词：山羊 皮下脓肿 金黄色葡萄球菌 伪结核棒状杆菌 球虫 

分 类 号：S858.27[农业科学—临床兽医学]