1,1,1,3,3-五氟丁烷的连续生产工艺研究  

Study on Continuous Production Process of 1,1,1,3,3-Pentafluorobutane

作　　者：熊显云 苏艳丽 贺爱国 邓聪 XIONG Xianyun;SU Yanli;HE Aiguo;DENG Cong(Zhejiang Quhua Fluor-Chemistry Co.,Ltd.,Quzhou 324000,China;Zhejiang Liangqiang Environmental Engineering Co.,Ltd.,Hangzhou 311200,China)

机构地区：[1]浙江衢化氟化学有限公司,浙江衢州324000 [2]浙江联强环境工程技术有限公司,浙江杭州311200

出　　处：《有机氟工业》2024年第2期3-7,共5页Organo-Fluorine Industry

摘　　要：以较低纯度的1,1,1,3,3-五氯丁烷(HCC-360jfa)和无水氟化氢(AHF)为原料,在较温和条件下通过氟化反应制备了1,1,1,3,3-五氟丁烷(HFC-365mfc)。对投料物质的量比、催化剂用量、反应温度、压力等工艺参数进行了优化。结果表明:HFC-365mfc连续生产的最佳工艺条件为n(AHF)∶n(HCC-360jfa)为14∶1,反应温度80~90℃,反应压力0.40~0.55 MPa,催化剂起始浓度2.0%。对于此类氟化反应中遇到的一些实际问题,也给出了解决方案和对策。1,1,1,3,3-Pentafluorobutane(HFC-365mfc)was prepared by fluorination with high purity 1,1,1,3,3-pentachlorobutane(HCC-360jfa)and anhydrous hydrogen fluoride(AHF)as raw materials under mild conditions.Process parameters such as the ratio of feed materials,catalyst dosage,reaction temperature,and pressure have been optimized.The results showed that the optimal parameters for continuous production of HFC-365mfc were n(AHF):n(HCC-360jfa)at 14:1,reaction temperature of 80~90℃,reaction pressure of 0.40~0.55 MPa,and catalyst initial concentration of 2.0%.There are some problems in this kind of fluorination,and the solutions and countermeasures were given in this paper.

关 键 词：HFC-365MFC 1 1 1 3 3-五氟丁烷 氟化工 工艺优化 

分 类 号：TQ222.213[化学工程—有机化工]