乙醇醛合成及应用研究进展  

Research Progress on Glycolaldehyde Synthesis and Application

作　　者：邓永智 陈佳乐 李春祥 姜晓晓 尹秀莲 张金峰 DENG Yong-zhi;CHEN Jia-le;LI Chun-xiang;JIANG Xiao-xiao;YIN Xiu-lian;ZHANG Jin-feng(Faculty of Life Science and Food Engineering,Huaiyin Institute of Technology,Jiangshu Huaian 223003;Jiangsu Province Probiotics Key Construction Laboratory,Jiangshu Huaian 223003,China)

机构地区：[1]淮阴工学院生命科学与食品工程学院,江苏淮安223003 [2]江苏省益生制剂重点建设实验室,江苏淮安223003

出　　处：《广州化工》2024年第9期6-8,共3页GuangZhou Chemical Industry

基　　金：淮安市重点研发计划(工业类):微生物酶法区域选择性氧化尼莫克汀合成莫西菌素的新工艺研发(编号:HAG202107)。

摘　　要：乙醇醛作为重要的化工中间体,被广泛的应用于食品、医药卫生、化工等行业。综述了乙醇醛的合成工艺路线,包括以甲醛为原料通过氢甲酰化法,选择性醛糖反应,生物催化法;以乙二醇为原料通过化学氧化法、生物催化法等。其中近年来随着现代生物技术的发展,以乙二醇为原料经生物催化合成乙醇醛的方法具有良好的前景。Glycolaldehyde,an important chemical intermediate,is widely used in food,medicine and health,chemical and other industries.Synthetic routes of glycolaldehyde were reviewed according to different starting materials,including formaldehyde by hydroformylation,selective aldose reaction,and biocatalytic reaction,as well as ethylene glycol by chemical and biological oxidation,etc.With the development of modern biotechnology,the biological methods of producing glycolaldehyde from ethylene glycol were increasingly promising.

关 键 词：乙醇醛 甲醛 乙二醇 生物氧化法 甲醛聚糖反应 

分 类 号：TQ914.1[化学工程]