《抗肿瘤药物临床应用管理标准》制订与解析  

Development and Analysis of the Standard for Management of Antineoplastic DrugsUse in Clinical

作　　者：张关敏[1] 张艳华[1] 甄健存 陈英[3] 张威 姜玲[4] 王建青 卢晓阳[6] 吕迁洲 张志清[8] 刘代华[9] 席加喜[3] ZHANG Guanmin;ZHANG Yanhua;ZHEN Jiancun;CHEN Ying;ZHANG Wei;JIANG Ling;WANG Jianqing;LU Xiaoyang;LYU Qianzhou;ZHANG Zhiqing;LIU Daihua;XI Jiaxi(Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing),Department of Pharmacy,Peking University Cancer Hospital and Institute,Beijing 100142,China;Department of Pharmacy,Beijing Jishuitan Hospital of Capital Medical University,Beijing 100035,China;Department of Pharmacy,the People’s Hospital of Guangxi Zhuang Autonomous Region,Nanning 530016,China;Department of Pharmacy,the First Affiliated Hospital of University of Science and Technology of China,Hefei 230031,China;Department of Pharmacy,the First Affiliated Hospital of Anhui Medical University,Hefei 230022,China;Department of Pharmacy,the First Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou 310003,China;Department of Pharmacy,Zhongshan Hospital Affiliated to Fudan University,Shanghai 200032,China;Department of Pharmacy,the Second Hospital of Hebei Medical University,Shijiazhuang 050000,China;Department of Pharmacy,the People’s Hospital Liuzhou City,Guangxi Zhuang Autonomous Region,Liuzhou 545006,China)

机构地区：[1]北京大学肿瘤医院暨北京市肿瘤防治研究所药剂科,恶性肿瘤发病机制及转化研究教育部重点实验室,北京100142 [2]首都医科大学附属北京积水潭医院药学部,北京100035 [3]广西壮族自治区人民医院药学部,南宁530016 [4]中国科学技术大学附属第一医院(安徽省立医院)药学部,合肥230031 [5]安徽医科大学第一附属医院药剂科,合肥230022 [6]浙江大学医学院附属第一医院药学部,杭州310003 [7]复旦大学附属中山医院药剂科,上海200032 [8]河北医科大学第二医院药学部,石家庄050000 [9]广西壮族自治区柳州市人民医院药学部,柳州545006

出　　处：《医药导报》2024年第8期1226-1229,共4页Herald of Medicine

基　　金：北京大学肿瘤医院教育教学研究课题(2023-JY-08)。

摘　　要：抗肿瘤药物是指通过细胞杀伤、免疫调控、内分泌调节等途径,在细胞、分子水平进行作用,达到抑制肿瘤生长或消除肿瘤的药物,一般包括化学治疗药物、分子靶向治疗药物、免疫治疗药物、内分泌治疗药物等。医疗机构对抗肿瘤药物的管理及合理应用,关系到肿瘤患者的治疗安全。《抗肿瘤药物临床应用管理标准》由中国医院协会药事专业委员会牵头编制,对医疗机构抗肿瘤药物管理工作中涉及的组织管理与制度、用药管理、药品监测与评价三个环节中的18个关键要素进行了规范要求,适用于开展肿瘤诊疗的各级各类医疗机构。该文阐述了该标准制定方法和基本内容,以期为医疗机构开展相关工作提供参考和借鉴。Antineoplastic drugs refer to the drugs that act at the cellular and molecular levels to inhibit tumor growth or eliminate tumors through pathways such as cell killing,immune regulation,and endocrine regulation.Antineoplastic drugs generally including chemotherapeutic drugs,molecular targeted therapeutic drugs,immunotherapeutic drugs,and endocrine therapeutic drugs.The management and rational application of antineoplastic drugs in medical institutions are related to the safety of patient treatment.The standard for management of antineoplastic drugs use in clinical is compiled by the Pharmaceutical Affairs Committee of China Hospital Association,which specification requirements 18 key elements in the organizational management and system,medication management,drug monitoring and evaluation of antineoplastic drug management in healthcare institutions.This standard is applicable to all levels and types of healthcare institutions carrying out oncology diagnosis and treatment.This paper describes the methodology and basic content of the standard,hoping to providing a reference for medical institutions to carry out relevant work.

关 键 词：抗肿瘤药物 标准制定 医疗机构药事管理 

分 类 号：R95[医药卫生—药学]