妊娠期肝内胆汁瘀积症患者脐动脉血流参数与胎儿宫内窘迫关系  

Correlation between the umbilical artery blood flow parameters values of pregnant women with intrahepatic cholestasis during pregnancy and their fetal distress occurrence

作　　者：王伟[1] 宋露 金小巍 WANG Wei;SONG Lu;JIN Xiaowei(Zaozhuang Maternal and Child Health Care Hospital,Zaozhuang,Shandong Province,277100)

机构地区：[1]山东省枣庄市妇幼保健院,277100

出　　处：《中国计划生育学杂志》2024年第7期1618-1620,共3页Chinese Journal of Family Planning

摘　　要：目的:探讨妊娠期肝内胆汁瘀积症(ICP)脐动脉血流参数与胎儿宫内窘迫的关系。方法:收集2018年3月-2021年3月于本院治疗的妊娠期肝内胆汁瘀积症患者101例临床资料为病例组,产前检查健康孕妇85例临床资料为对照组,以是否发生胎儿宫内窘迫将病例组分为宫内窘迫组和非宫内窘迫组,分析各组脐动脉血流参数水平及与胎儿宫内窘迫发生的相关性。结果:病例组脐动脉血流参数S/D(4.23±0.35)、RI(1.66±0.32)及PI(1.05±0.15)水平均高于对照组(3.61±0.25、1.01±0.21、0.74±0.23),胎儿宫内窘迫组高于无胎儿宫内窘迫组;相关性分析,脐动脉血流参数S/D、RI及PI与胎儿宫内窘迫发生呈正相关(均P<0.05)。结论:妊娠期肝内胆汁瘀积症患者脐动脉血流参数异常,且与发生胎儿宫内窘迫正相关,为临床病情控制有临床指导意义。Objective: To study the correlation between the umbilical artery blood flow parameters values of pregnant women with intrahepatic cholestasis during pregnancy(ICP) and their fetal distress occurrence. Methods: 101 pregnant women with ICP were selected in study group and 85 healthy pregnant women were selected in control group from March 2018 to March 2021. The women in the study group were divided into group A(women with fetal distress) and group B(women without fetal distress). The correlation between the umbilical artery blood flow parameters values of the women in these groups and their fetal distress was analyzed. Results: The values of S/D(4.23±0.35), RI(1.66±0.32) and PI(1.05±0.15) of the umbilical artery blood flow parameters of the women in the study group were significantly higher than those(3.61±0.25, 1.01±0.21 and 0.74±0.23) of the women in the control group, and which of the women in group A were significantly higher than those of the women in group B. Correlation analysis showed that the values of S/D, RI and PI of the umbilical artery blood flow of the women with ICP were positively correlated with their occurrence of fetal distress(all P<0.05). Conclusion: The umbilical artery blood flow parameters values of the pregnant women with ICP are abnormal, and are correlated with their fetal distress occurrence, and which has the clinical significance for gilding the ICP control of the pregnant women.

关 键 词：妊娠期肝内胆汁瘀积症 胎儿宫内窘迫 脐动脉血流参数 相关性 

分 类 号：R714.255[医药卫生—妇产科学]