尿毒症血液透析患者低血压发生现状及影响因素分析  

Analysis of the current status and influencing factors of hypotension in patients with uremic hemodialysis

作　　者：王娜娜[1] WANG Nana(Blood Purification Center,the Third People's Hospital of Zhengzhou,Zhengzhou 450003,China)

机构地区：[1]郑州市第三人民医院血液净化中心,河南郑州450003

出　　处：《临床医学研究与实践》2024年第21期13-16,共4页Clinical Research and Practice

摘　　要：目的探究尿毒症血液透析患者低血压发生现状及影响因素。方法选取2021年8月至2023年3月我院收治的118例尿毒症血液透析患者作为研究对象,回顾性分析患者的一般资料及实验室指标,统计其低血压发生情况,并采用Logistic回归分析探究患者低血压发生的影响因素。结果118例尿毒症血液透析患者发生低血压37例,发生率为31.36%,根据低血压发生情况将其分为发生组(n=37)和未发生组(n=81)。发生组合并糖尿病、低蛋白血症占比及超滤率均高于未发生组,透析前收缩压低于未发生组,透析时间长于未发生组,差异具有统计学意义(P<0.05)。多因素Logistic回归分析显示,合并糖尿病、合并低蛋白血症、超滤率、透析时间是尿毒症血液透析患者低血压发生的危险因素,透析前收缩压是其保护因素(P<0.05)。结论尿毒症血液透析患者低血压发生率较高,其发生与合并糖尿病、合并低蛋白血症、超滤率、透析前收缩压、透析时间相关,临床可据此针对性制定干预措施以减少低血压发生。Objective To investigate the current status and influencing factors of hypotension in patients with uremic hemodialysis.Methods A total of 118 patients with uremic hemodialysis admitted in our hospital from August 2021 to March 2023 were selected as the research objects.The general data and laboratory indexes of the patients were retrospectively analyzed,and the occurrence of hypotension was counted.Logistic regression analysis was used to explore the influencing factors of hypotension in patients.Results There were 37 cases of hypotension in 118 uremic hemodialysis patients,with an occurrence of 31.36%.According to the occurrence of hypotension,the patients were divided into occurrence group(n=37)and non-occurrence group(n=81).The proportion of diabetes,hypoproteinemia and ultrafiltration rate in the occurrence group were higher than those in the non-occurrence group,the systolic blood pressure before dialysis was lower than that in the non-occurrence group,and the dialysis time was longer than that in the non-occurrence group,the differences were statistically significant(P<0.05).Multivariate Logistic regression analysis showed that diabetes,hypoproteinemia,ultrafiltration rate and dialysis time were risk factors for hypotension in patients with uremic hemodialysis,and systolic blood pressure before dialysis was a protective factor(P<0.05).Conclusion The occurrence of hypotension in patients with uremic hemodialysis is high,which is related to diabetes,hypoproteinemia,ultrafiltration rate,systolic blood pressure before dialysis and dialysis time,clinical intervention measures can be formulated accordingly to reduce the occurrence of hypotension.

关 键 词：尿毒症 血液透析 低血压 

分 类 号：R544.2[医药卫生—心血管疾病]