多糖铁胶囊联合饮食指导对预防妊娠期缺铁性贫血发生的临床研究  

Clinical study of polysaccharide iron capsule combined with dietary guidance on prevention of iron deficiency anemia during pregnancy

作　　者：周莉莉 Zhou Lili(Department of Obstetrics and Gynecology,Dawangzhuang Street Community Health Service Center,Hedong District,Tianjin 300171,China)

机构地区：[1]天津市河东区大王庄街社区卫生服务中心,天津300171

出　　处：《首都食品与医药》2024年第12期78-80,共3页Capital Food Medicine

摘　　要：目的探讨多糖铁胶囊联合饮食指导对妊娠期缺铁性贫血的预防效果。方法于2022年10月-2023年5月来诊的孕妇中选取42例铁缺乏孕妇,按照随机数字表法分为对照组(n=21,配合饮食指导)和观察组(n=21,配合饮食指导同时加用多糖铁胶囊),比较两组总有效率、铁缺乏与缺铁性贫血发生率、铁代谢参数、血常规、妊娠结局、不良反应。结果观察组总有效率为95.24%,比对照组高(P<0.05)。孕28周时,观察组铁缺乏率为4.76%、缺铁性贫血发生率为0.00%,比对照组低(P<0.05)。治疗前比较,两组铁代谢参数、血常规无明显差异(P>0.05);治疗后两组铁蛋白(SF)、红细胞计数(RBC)、血红蛋白(Hb)均升高,并且观察组治疗后SF、RBC、Hb比对照组高(P<0.05)。观察组早产率9.52%、产后出血发生率14.29%、低出生体重新生儿9.52%,比对照组低(P<0.05)。观察组便秘、头晕、疲惫乏力、心悸等不良反应总发生率33.33%与对照组的23.81%比较,无明显差异(P>0.05)。结论铁缺乏孕妇给予饮食指导同时加用多糖铁胶囊,能够显著改善铁代谢及血常规水平,降低缺铁性贫血发生风险,预防不良妊娠结局,临床效果确切,且未出现严重不良反应,安全性高。Objective To observe and discuss the preventive effect of polysaccharide iron capsule combined with dietary guidance on iron deficiency anemia during pregnancy.Methods From October 2022 to May 2023,42 pregnant women with iron deficiency were diagnosed and included in the control group(n=21,combined with dietary guidance)and observation group(n=21,combined with dietary guidance and supplemented with polysaccharide iron capsules)according to random number table method.The total effective rate,incidence of iron deficiency and iron deficiency anemia,iron metabolism parameters,blood routine,pregnancy outcome and adverse reactions were compared between the two groups.Results The total effective rate of observation group was 95.24%,which was higher than that of control group(P<0.05).At 28 weeks of pregnancy,the iron deficiency rate was 4.76%and the incidence of iron deficiency anemia was 0.00%in the observation group,which was lower than that in the control group(P<0.05).Before treatment,there were no differences in iron metabolism parameters and blood routine between the two groups(P>0.05).Ferritin(SF),red blood cell count(RBC)and hemoglobin(Hb)of the two groups were increased after treatment,and the SF,RBC and Hh of the observation group were higher than those of the control group after treatment(P<0.05).The preterm birth rate of 9.52%,postpartum hemorrhage rate of 14.29%and low birth weight of 9.52%in the observation group were lower than those in the control group(P<0.05).The total incidence of adverse reactions such as constipation,dizziness,fatigue and palpitation in the observation group was 33.33%and 23.81%in the control group(P>0.05).Conclusion Dietary guidance for iron-deficient pregnant women combined with polysaccharide iron capsule can significantly improve iron metabolism and blood routine levels,reduce the risk of iron-deficiency anemia,and prevent adverse pregnancy outcomes.The clinical effect is accurate,and no serious adverse reactions occur,and the safety is high.

关 键 词：妊娠期缺铁性贫血 多糖铁胶囊 饮食指导 铁代谢 妊娠结局 

分 类 号：R556.3[医药卫生—血液循环系统疾病]