冻融胚胎移植前IVF-ET助孕患者的血清E_(2)、孕酮表达情况及其与妊娠结局的相关性分析  

Analysis on Serum E_(2)and Progesterone Expressions in IVF-ET Assisted Pregnancy Patients before Frozen-Thawed Embryo Transfer and the Correlation with Pregnancy Outcomes

作　　者：熊维玲 刘梦伊 魏晓瑞 廖美光 于海微[4] XIONG Weiling;LIU Mengyi;WEI Xiaorui;LIAO Meiguang;YU Haiwei(Department of Reproductive Medicine,Xiamen Anbao Hospital,Xiamen 361004,China;Embryo Laboratory,Xiamen Anbao Hospital,Xiamen 361004,China;Department of Gynecology,Xiamen Traditional Chinese Medicine Hospital,Xiamen 361009,China;Department of Obstetrics,Xiamen Traditional Chinese Medicine Hospital,Xiamen 361009,China)

机构地区：[1]厦门安宝医院生殖医学科,福建厦门361004 [2]厦门安宝医院胚胎实验室,福建厦门361004 [3]厦门市中医院妇科,福建厦门361009 [4]厦门市中医院产科,福建厦门361009

出　　处：《临床医学工程》2024年第7期847-848,共2页Clinical Medicine & Engineering

摘　　要：目的分析冻融胚胎移植前体外受精-胚胎移植(IVF-ET)助孕患者的血清雌二醇(E_(2))、孕酮表达情况及其与妊娠结局的相关性。方法选择2020年3月至2022年3月收治的126例IVF-ET助孕患者,冻融胚胎移植前检测血清E_(2)、孕酮表达情况,完成IVF-ET助孕后统计妊娠结局,比较不同妊娠结局患者冻融胚胎移植前血清E_(2)、孕酮表达,并分析冻融胚胎移植前IVF-ET助孕患者的血清E_(2)、孕酮表达与妊娠结局的相关性。结果126例IVF-ET助孕患者妊娠成功51例,成功率为40.48%。妊娠失败患者冻融胚胎移植前血清E_(2)、孕酮低于妊娠成功患者(P<0.05)。经Logistic回归分析结果显示,血清E_(2)、孕酮表达与妊娠结局有关(P<0.05)。结论IVF-ET助孕患者的妊娠结局与冻融胚胎移植前血清E_(2)、孕酮表达密切相关。Objective To analyze the serum estradiol(E_(2))and progesterone expressions of in vitro fertilization embryo transfer(IVF-ET)assisted pregnancy patients before frozen-thawed embryo transfer and the correlation with pregnancy outcomes.Methods 126 IVF-ET assisted pregnancy patients from March 2020 to March 2022 were selected.The serum E_(2)and progesterone expressions were detected before frozen-thawed embryo transfer,and the pregnancy outcomes were counted after completing IVF-ET assisted pregnancy.The serum E,and progesterone expressions of patients with different pregnancy outcomes before frozen-thawed embryo transfer were compared,and the correlation between the serum E_(2),progesterone expressions and pregnancy outcomes was analyzed.Results 51 out of 126 IVF-ET assisted pregnancy patients were successful,with the success rate of 40.48%.The serum E_(2)and progesterone of failed pregnancy patients before frozen-thawed embryo transfer were lower than those of successful pregnancy patients(P<0.05).Logistic regression analysis results showed that the serum E_(2)and progesterone expressions were correlated with pregnancy outcomes(P<0.05).Conclusions The pregnancy outcomes of IVF-ET assisted pregnancy patients are closely correlated with the serum E_(2)and progesterone expression before frozen-thawed embryo transfer.

关 键 词：体外受精-胚胎移植 冻融胚胎 雌二醇 孕酮 

分 类 号：R714.8[医药卫生—妇产科学]