新外来中药非洲马铃果皮的药性研究  

Medicinal Properties of the Bark of Voacanga africana in Chinese Medicine

作　　者：姜砚馨 张惠 费文婷 王淳[1] 裴欢[2] 刘曦[2] 郭宝林[3] 王林元[1] 奥恰·巴尔纳巴斯 夏立营[5] 张建军[1] JIANG Yanxin;ZHANG Hui;FEI Wenting;WANG Chun;PEI Huan;LIU Xi;GUO Baolin;WANG Linyuan;Oche E.Barnabas;XIA Liying;ZHANG Jianjun(Beijing University of Chinese Medicine,Beijing 100029,China;Beijing Peking University Wbl Biotech Co.,Ltd.,Beijing 100094,China;Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100193,China;Nigeria Natural Medicine Development Agency,Lagos State 101241,Nigeria;Chinese Medical Health Care and Research Center,Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091,China)

机构地区：[1]北京中医药大学,北京100029 [2]北京北大维信生物科技有限公司,北京100094 [3]中国医学科学院北京协和医学院药用植物研究所,北京100193 [4]尼日利亚自然医学发展局,尼日利亚拉各斯州101241 [5]中国中医科学院西苑医院中医药保健研究中心,北京100091

出　　处：《世界中医药》2024年第11期1537-1543,共7页World Chinese Medicine

基　　金：国家重点研发计划中医药现代化研究重点专项(2018YFC1706800);国家中医药管理局国际合作司中医药国际合作专项(基地类项目)(0730-236132ZC0054/01~03);国家中医药管理局国际合作司中医药国际合作专项(中心类项目)(0730-236132ZC0052/01~04)。

摘　　要：目的:分析非洲马铃果皮的中药药性,为促进非洲马铃果作为外来中药引入中国,实现其与传统中药配伍应用提供理论依据。方法:选用科学期刊文献数据库进行检索,对相关文献进行纳入、排除、分类及统计。结合中医药理论探讨非洲马铃果皮的中药药性,总结分析相关历史应用、化学成分、药理活性等研究。结果:非洲马铃果皮为夹竹桃科马铃果属植物非洲马铃果(Voacanga africana Stapf)的根皮和树皮,中药药性为味苦、甘,性凉,归脾、胃、心、肝经,具有清热燥湿、解毒止痢、镇惊安神、止痉止痛之功。可用于热毒血痢、休息痢,呆钝健忘,胃脘痛、睾丸肿痛、痛经、跌打伤痛、惊厥等。水煎服,10~25 g/d,无毒。结论:研究赋予非洲马铃果皮中药药性,可为其引入中医临床并进一步与中药配伍应用奠定理论基础,同时对丰富我国中药资源、促进中医药可持续发展有重要意义。Objective:To analyze the medicinal properties of the bark of Voacanga africana in Chinese medicine and provide a theoretical basis for its introduction into China as an exotic medicinal herb,facilitating its combination with traditional Chinese herbs.Methods:Scientific journal databases were used for literature retrieval.Relevant literature was included,excluded,classified,and statistically analyzed.The medicinal properties of the bark of V.africana were explored based on traditional Chinese medicine(TCM)theories,and relevant historical applications,chemical components,and pharmacological activities were summarized and analyzed.Results:The bark of V.africana from the Apocynaceae family has medicinal properties characterized as bitter and sweet in flavor,and cool in nature,and acts on the spleen,stomach,heart,and liver meridians.It has the functions of clearing heat,drying dampness,removing toxin,stopping dysentery,calming the mind,stopping spasms,and relieving pain,and can be used for conditions such as heat-toxic dysentery,chronic dysentery,mental dullness and forgetfulness,epigastric pain,testicular swelling and pain,dysmenorrhea,traumatic injuries,and convulsions.It is used in decoction at recommended dosage of 10 to 25 g/day,and is non-toxic.Conclusion:The study attributes medicinal properties to the bark of V.africana,providing a theoretical foundation for its introduction into TCM clinical practice and its combination with other Chinese herbs,and it is significant for enriching Chinese medicinal resources and promoting the sustainable development of TCM.

关 键 词：非洲马铃果 中药药性 外来中药 功能主治 性味归经 药用历史 药理作用 化学成分 

分 类 号：R285.1[医药卫生—中药学]