基于文献回顾探讨中医药对A群链球菌免疫逃逸机制的影响  

Discussion Through Literature Review about Effects of Chinese Medicine on Immune Escape Mechanism of Group A Streptococcus

作　　者：尹延重 YIN Yanzhong(Infection disease department,First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300381,China;National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion,Tianjin 300381,China)

机构地区：[1]天津中医药大学第一附属医院感染疾病科,天津300381 [2]国家中医针灸临床医学研究中心,天津300381

出　　处：《实用中医内科杂志》2024年第7期111-114,共4页Journal of Practical Traditional Chinese Internal Medicine

基　　金：天津中医药大学第一附属医院拓新工程科研基金项目(院2020050)。

摘　　要：A群链球菌(group A streptococcus,GAS)能够引起各种化脓性感染性疾病,感染呈反复迁延趋势,如丹毒、扁桃体炎等,给患者的生活及工作带来极大的痛苦,增加了社会医疗经济负担,反复抗生素使用造成抗生素多重耐药等多种严重问题。相关文献研究发现GAS的反复严重感染与其免疫逃逸机制具有重要相关性,因此对GAS免疫逃逸机制进行初步探究;GAS导致的丹毒、扁桃体炎等呈反复发作趋势,经过相关中医文献研究,中医药对预防及治疗丹毒、扁桃体炎等反复发作有着良好效果,因此进一步探讨中医药对GAS免疫逃逸机制的影响。Group a streptococcus(GAS)can cause all kinds of suppurative infectious diseases,and the infection shows a tendency of repeated delay,such as erysipelas,tonsillitis and so on,which brings great pain to the life and work of patients,and increases the economic burden of social medical treatment,multiple serious problems caused by repeated antibiotic use.The repeated severe infection of gas has important correlation with its immune escape mechanism,so the mechanism of immune escape of gas is preliminarily explored;The acute infection of intradermal reticular lymphatic vessels caused by streptococcus a group of erysipelas,most of the patients showed a tendency of recurrent attacks.Through the study of relevant literature of traditional Chinese medicine,Chinese medicine has a good effect on the prevention and treatment of recurrent episodes of erythritory,so it is necessary to further explore the intervention mechanism of immune escape in GAS based on traditional Chinese medicine.

关 键 词：A群链球菌 免疫逃逸 丹毒 中医药 

分 类 号：R285[医药卫生—中药学]