住院老年患者肌少症患病情况及其影响因素分析  

Prevalence and associated factors of sarcopenia in hospitalized older patients

作　　者：马玲玲[1] 刘洪伯 徐锐[3] 王红梅[4] MA Lingling;LIU Hongbo;XU Rui;WANG Hongmei(Xinjiang Medical University,Urumqi 830054,China;不详)

机构地区：[1]新疆医科大学,乌鲁木齐830054 [2]新疆维吾尔自治区人民医院肿瘤科 [3]新疆维吾尔自治区人民医院老年医学中心 [4]新疆维吾尔自治区人民医院干部保健二科

出　　处：《中国临床保健杂志》2024年第3期342-346,共5页Chinese Journal of Clinical Healthcare

基　　金：新疆维吾尔自治区自然科学基金面上项目(2021D01C162)。

摘　　要：目的探讨住院老年患者肌少症患病情况及其影响因素。方法选取2022年5月至2023年4月新疆维吾尔自治区人民医院符合纳入条件的309例住院老年患者作为研究对象。收集患者人口学资料及慢性病、实验室检查指标,采用抑郁症筛查量表、广泛性焦虑自评量表、国际疼痛研究协会慢性疼痛诊断标准、阿森斯失眠量表、微型营养评估量表、简易智能精神状态检查量表评估患者抑郁、焦虑、疼痛、睡眠、营养及认知功能。根据2019年亚洲肌少症工作组标准诊断肌少症,将患者分为肌少症组49例和非肌少症组260例,比较2组患者临床资料,采用二元logistic回归分析住院老年患者肌少症的影响因素。结果309例住院老年患者中肌少症患病率为15.9%,≥80岁患者肌少症患病率为33.7%。肌少症组与非肌少症组患者在年龄、体重指数、营养状态、认知功能、运动、高血压、冠心病、慢性心力衰竭、慢性阻塞性肺疾病、血清白蛋白、血红蛋白、估算肾小球滤过率、三酰甘油、总胆固醇、低密度脂蛋白胆固醇比较,差异有统计学意义(P<0.05)。二元logistic回归分析结果显示:缺乏运动(OR=3.207,95%CI:1.370~7.509)、冠心病(OR=3.677,95%CI:1.497~9.029)是住院老年患者肌少症发生的危险因素(P<0.05),体重指数增加(OR=0.732,95%CI:0.617~0.869)是住院老年患者肌少症的保护因素(P<0.05)。结论住院老年患者中肌少症患病率较高,低体重指数、缺乏运动、患有冠心病的住院老年患者肌少症患病风险增加。Objective To investigate the sarcopenia prevalence and associated factors in the hospitalized older patients.Methods A total of 309 older inpatients eligible for inclusion in People′s Hospital of Xinjiang Uygur Autonomous region from May 2022 to April 2023 were selected as the study objects.Their demographic data,chronic diseases and laboratory test indicators were collected.The prevalence of depression assessed by the Depression Screening Scale,anxiety assessed by the Generalized Self-Rating Anxiety Scale,pain assessed by the International Association for the Study of Pain,sleep assessed by the Athens Insomnia Scale,nutrition assessed by the Mininutrition Assessment Scale,and cognitive function assessed by the Simple Intelligent Mental State Examination Scale.Sarcopenia was diagnosed according to the diagnostic criteria of the Asian Sarcopenia Working Group in 2019,and the patients were divided into the sarcopenia group(49 cases)and the non-sarcopenia group(260 cases).Binary logistic regression analysis was performed to identify the factors associated with sarcopenia.Results The prevalence of sarcopenia was 15.9%in 309 older inpatients,And the prevalence of sarcopenia in patients≥80 years old was 33.7%。There were significant differences in age,BMI,nutritional status,cognitive function,exercise,hypertension,coronary heart disease,chronic heart failure,chronic obstructive pulmonary disease,Alb,Hb,eGFR,TG,TC and LDL-C between the sarcopenia group and the non-sarcopenia group(P<0.05).Binary logistic regression analysis results showed:lack of exercise(OR=3.207,95%CI:1.370-7.509)and coronary heart disease(OR=3.677,95%CI:1.497-9.029)were the risk factors for sarcopenia in older hospitalized patients(P<0.05).Increased BMI(OR=0.732,95%CI:0.617-0.869)was a protective factor for sarcopenia in older hospitalized patients(P<0.05).Conclusions The prevalence of sarcopenia is higher in hospitalized elderly patients.The risk of sarcopenia in hospitalized older patients with low BMI,lack of exercise and coronary heart disea

关 键 词：肌减少症 患病率 住院病人 危险因素 老年人 

分 类 号：R685[医药卫生—骨科学]