颈动脉超声评估青年2型糖尿病颈动脉病变的应用价值研究  

Application Value of Carotid Ultrasound in Evaluating Carotid Artery Disease in Young Patients with Type 2 Diabetes Mellitus

作　　者：杨燕 高宏霞 Yang Yan;Gao Hongxia(The Affiliated Hospital of Gansu Medical College,Pingliang 744000,Gansu Province,China)

机构地区：[1]甘肃医学院附属医院,甘肃平凉744000

出　　处：《中外医药研究》2024年第17期138-140,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

基　　金：2021年甘肃省高等学校创新基金项目《基于颈动脉超声的青年2型糖尿病患者多维度危险因素分析及大血管并发症的干预研究》(编号:2021-A184)。

摘　　要：目的:研究颈动脉超声检查在青年2型糖尿病患者中的应用价值。方法:选取2022年1月—2023年12月甘肃医学院附属医院收治的青年2型糖尿病患者254例作为研究对象,根据冠状动脉造影结果将患者分为对照组(单纯糖尿病)和观察组(糖尿病合并颈动脉粥样硬化)。所有患者实施颈动脉超声检查,比较两组内-中膜厚度(IMT)、斑块情况、血管硬化程度及诊断价值。结果:观察组颈总动脉、颈内动脉、颈总动脉分叉处IMT大于对照组,差异有统计学意义(P<0.05);观察组检出斑块数、易损斑块占比及斑块厚度高于对照组,差异有统计学意义(P<0.05);观察组稳定斑块占比低于对照组,差异有统计学意义(P<0.05);两组斑块长度比较,差异无统计学意义(P>0.05);观察组弹性系数、顺应性、颈总动脉硬化度、脉搏波传导速度高于对照组,差异有统计学意义(P<0.05)。颈动脉超声诊断易损斑块的灵敏度为81.45%(101/124),特异度为92.06%(58/63)。结论:颈动脉超声在青年2型糖尿病患者中具有较高的诊断价值,可以有效发现患者的颈动脉病变情况,通过颈动脉超声检查可以对患者的病情进行有效的评估。Objective:To study the application value of carotid ultrasound in young patients with type 2 diabetes.Methods:A total of two hundred and fifty-four young patients with type 2 diabetes admitted to the Affiliated Hospital of Gansu Medical College from January 2022 to December 2023 were selected as the study objects.According to the results of coronary angiography,the patients were divided into control group(diabetes alone)and observation group(diabetes with carotid atherosclerosis).Carotid ultrasound was performed in all patients,and the endo-media thickness(IMT),plaque status,degree of vascular sclerosis and diagnostic value were compared between the two groups.Results:The IMT of common carotid artery,internal carotid artery and common carotid artery bifurcation in observation group was higher than that in control group,the difference was statistically significant(P<0.05);the number of plaques,the proportion of vulnerable plaques and the thickness of plaques in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05);the proportion of stable plaque in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05);there was no significant difference in the length of plaques between the two groups(P>0.05);the elasticity coefficient,compliance,total carotid arteriosclerosis degree and pulse wave conduction velocity of observation group were higher than those of control group,and the differences were statistically significant(P<0.05);the sensitivity and specificity of carotid ultrasound in the diagnosis of vulnerable plaque were 81.45%(101/124)and 92.06%(58/63).Conclusion:Carotid ultrasound has a high diagnostic value in young patients with type 2 diabetes,and can effectively detect the condition of patients with carotid artery lesions,and can effectively evaluate the condition of patients through carotid ultrasound.

关 键 词：2型糖尿病 青年 动脉粥样硬化 颈动脉超声 评估价值 

分 类 号：R445.1[医药卫生—影像医学与核医学] R587.1[医药卫生—诊断学]