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作 者:陈晓敏 何君珍 吴惠玲 CHEN Xiaomin;HE Junzhen;WU Huiling(Department of Psychiatry,Lishui Second People's Hospital,Lishui 323000,Zhejiang,China)
机构地区:[1]丽水市第二人民医院精神科,浙江丽水323000
出 处:《辽宁中医杂志》2024年第7期68-71,共4页Liaoning Journal of Traditional Chinese Medicine
摘 要:目的 探究柴胡疏肝汤联合无抽搐电休克(MECT)在女性躯体化障碍患者中的应用效果。方法 将2021年6月—2022年6月该院收治的84例女性躯体化障碍患随机分为对照组42例和试验组42例。对照组予以MECT联合常规西药治疗,试验组在对照组基础上联合柴胡疏肝汤治疗。比较两组治疗前后临床症状、汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)评分、症状自评量表(SCL-90)各因子评分,评价两组的临床疗效及安全性。结果 治疗后两组临床症状均减轻,且试验组临床症状较对照组缓解更显著(P<0.05);治疗后,两组HAMD、HAMA评分均降低,且试验组低于对照组(P<0.05);治疗后,两组SCL-90各因子评分均降低,且试验组低于对照组(P<0.05);试验组的临床疗效优于对照组(P<0.05);两组不良反应总发生率比较差异不明显(P>0.05)。结论 对女性躯体化障碍患者应用柴胡疏肝汤联合MECT治疗,可显著改善患者的临床症状,缓解其神经症状,促进其病情转归,提升其治疗效果,且安全性高。Objective To explore the effect of Chaihu Shugan Decoction(柴胡疏肝汤)combined with non-convulsive electroconvulsive therapy(MECT)in female patients with somatization disorder.Methods Eighty-four female patients with somatization disorders admitted to the hospital from June 2021 to June 2022 were randomly divided into control group(42 cases)and test group(42 cases).The control group was treated with MECT combined with conventional western medicine,while the test group was treated with Chaihu Shugan Decoction on the basis of the control group.The scores of clinical symptoms,Hamilton Depression Scale(HAMD),Hamilton Anxiety Scale(HAMA)and Symptom Checklist 90(SCL-90)before and after treatment were compared between the two groups to evaluate the clinical efficacy and safety of the two groups.Results After treatment,the clinical symptoms of the two groups were alleviated,and the clinical symptoms of the test group were alleviated more significantly than those of the control group(P<0.05).After treatment,the scores of HAMD and HAMA in both groups decreased,and the scores of the test group were lower than those of the control group(P<0.05).After treatment,each factor score of SCL-90 in the two groups decreased,and the score of the test group was lower than that of the control group(P<0.05).The clinical efficacy of the test group was better than that of the control group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Chaihu Shugan Decoction combined with MECT can significantly improve the clinical symptoms of female patients with somatization disorder,relieve their neurological symptoms,promote the prognosis of their condition and improve their treatment effect,with high safety.
关 键 词:女性躯体化障碍 柴胡疏肝汤 无抽搐电休克 临床症状 神经症状 疗效 安全性
分 类 号:R271[医药卫生—中医妇科学]
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