蜂疗相关药物治疗阿尔兹海默症的作用机制研究进展  

Research Progress on the Mechanisms of Apitherapy-Related Drugs in the Treatment of Alzheimer's Disease

作　　者：刘舒[1] 孙跃峰 李抒凝 陈晶[1] LIU Shu;SUN Yuefeng;LI Shuning;CHEN Jing(Heilongjiang University of Chinese Medicine,Harbin 150040)

机构地区：[1]黑龙江中医药大学,哈尔滨150040

出　　处：《中药药理与临床》2024年第5期122-128,共7页Pharmacology and Clinics of Chinese Materia Medica

基　　金：国家自然科学基金(编号:82274395);黑龙江省省属本科高校改革发展资金项目(编号:2021CZT01);黑龙江中医药大学研究生创新科研项目(编号:2022yjscx001)。

摘　　要：阿尔茨海默症是一种与年龄相关的、多因素导致的神经退行性疾病,现有药物治疗结果不尽如人意。因此,急需寻找可以靶向其病理学各种潜在机制并减少疾病发生发展的药物。蜂疗相关药物治疗阿尔茨海默症疗效确切,文章对近年来蜂疗相关药物治疗阿尔茨海默症的作用机制进行综述,以期为其更深入的研究提供参考。Alzheimer's disease is an age-related neurodegenerative disorder that is caused by multiple factors.The current drug treatments for Alzheimer's disease have been unsatisfactory.Therefore,there is an urgent need to find drugs that can target the various underlying mechanisms of its pathology and reduce the occurrence and progression.Apitherapy-related drugs have shown promising therapeutic effects for Alzheimer's disease.This article provided an overview of the mechanisms of apitherapy-related drugs in the treatment of Alzheimer's disease in recent years,aiming to provide references for further research in this area.

关 键 词：蜂疗相关药物 阿尔兹海默症 作用机制 乙酰胆碱酯酶 神经炎症 氧化损伤 凋亡 

分 类 号：R285[医药卫生—中药学]