白英清脉合剂治疗急性丹毒的疗效观察  

Clinical Efficacy Observation on Baiying Qingmai Mixture in Treating Acute Erysipelas

作　　者：方超 谢沛霖[1] 任君文 刘金伟[1] Fang Chao;Xie Peilin;Ren Junwen;Liu Jinwei(Wuhan First Hospital,Hubei,Wuhan 430000,China)

机构地区：[1]湖北省武汉市第一医院,湖北武汉430000

出　　处：《中国中医急症》2024年第7期1197-1200,共4页Journal of Emergency in Traditional Chinese Medicine

基　　金：武汉市中医药科研项目(S202204210071)。

摘　　要：目的观察加用白英清脉合剂治疗急性丹毒的临床疗效方法66例患者按照随机数字表法分为试验组与对照组各33例,试验组在抗生素联合硫酸镁外敷基础上加用白英清脉合剂内服,对照组给予抗生素联合硫酸镁外敷治疗,比较两组疼痛缓解时间、消肿时间、住院周期、中医证候积分、临床疗效、白细胞计数(WBC)、中性粒细胞百分比、红细胞沉降率(ESR)、C反应蛋白(CRP)水平以及中远期疗效。结果试验组疼痛缓解时间、消肿时间、住院周期短于对照组(P<0.05),中医证候积分低于对照组(P<0.05);试验组患者的WBC、中性粒细胞百分比、ESR、CRP水平低于对照组。院外随访结果示,试验组的后遗症发生率(水肿、疼痛、色素沉着及脂膜炎、溃疡)均低于对照组,差异有统计学意义(P<0.05);试验组6个月以上中远期复发率低于对照组(P<0.05)。结论白英清脉合剂内服治疗急性丹毒临床疗效显著,能有效降低后遗症发生率和复发率。Objective:To observe the clinical efficacy of adding Baiyin Qingmai Mixture in the treatment of acute erysipelas.Methods:Clinical data of 66 patients with acute erysipelas admitted were retrospectively ana⁃lyzed.The patients were divided into an experimental group(n=33)and a control group(n=33)using the random number table method.The experimental group received additional oral administration of Baiyin Qingmai Mixture on top of conventional antibiotics and topical magnesium sulfate,while the control group received antibiotics and topical magnesium sulfate alone.The two groups were compared in terms of pain relief time,edema resolution time,hospitalization duration,TCM syndrome score,clinical efficacy,white blood cell count,percentage of neutro⁃phils,erythrocyte sedimentation rate(ESR),C-reactive protein(CRP)level,and long-term treatment outcome.Re⁃sults:The experimental group had shorter pain relief time,edema resolution time,and hospitalization duration compared with the control group(P<0.05).The TCM syndrome score was lower in the experimental group(P<0.05).The white blood cell count,percentage of neutrophils,ESR,and CRP level were lower in the experimental group compared with the control group.Follow-up results outside the hospital showed that the incidence of compli⁃cations(edema,pain,pigmentation,and lipodermatitis,ulceration)was lower in the experimental group,with statisti⁃cally significant differences(P<0.05).The recurrence rate over six months in the experimental group was lower than that in the control group(P<0.05).Conclusion:The addition of oral Baiying Qingmai Mixture in the treat⁃ment of acute erysipelas demonstrated significant clinical efficacy.

关 键 词：丹毒 白英清脉合剂 硫酸镁外敷 中医药治疗 

分 类 号：R753.5[医药卫生—皮肤病学与性病学]