基于“络损脉痹”理论辨治糖尿病周围神经病变思路探析  

An Analysis on the Treatment of Diabetic Peripheral Neuropathy based on the Theory of“Collateral Damage and Pulse Arthralgia”

作　　者：许成群 方朝晖[2] 叶山东 费爱华[4] 鲍陶陶[2] 李家云[2] XU Chengqun;FANG Chaohui;YE Shandong;FEI Aihua;BAO Taotao;LI Jiayun(Huaibei City Hospital of Traditional Chinese Medicine,Anhui Huaibei 235000,China;The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine,Anhui Hefei 230031,China;The First Affiliated Hospital of University of Science and Technology of China,Anhui Hefei 230001,China;The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine,Anhui Hefei 230061,China)

机构地区：[1]安徽省淮北市中医医院,安徽淮北235000 [2]安徽中医药大学第一附属医院,安徽合肥230031 [3]中国科学技术大学附属第一医院,安徽合肥230001 [4]安徽中医药大学第二附属医院,安徽合肥230061

出　　处：《中医药临床杂志》2024年第7期1218-1222,共5页Clinical Journal of Traditional Chinese Medicine

基　　金：安徽省重大疑难疾病(糖尿病)中西医协同攻关项目:皖中医发展秘[2021]70号-6。

摘　　要：“络损脉痹”是糖尿病周围神经病变(DPN)的病机关键。气阴两虚、肝肾亏虚、湿热伤络、痰瘀阻络等是形成该病的主要原因。研究显示,养络通痹方药具有减轻炎症反应、修复神经功能、改善血液流变性、调节生长因子等作用,深入研究DPN“络损脉痹”的病因病机及养络通痹法的作用机理,对提高DPN的防治水平具有重要的临床意义。“Collateral damage and pulse arthralgia”is the key pathogenesis of(DPN.)Qi-Yin Deficiency,deficiency of liver and kidney,dampness-heat injury of collaterals and phlegm stasis blocking collaterals are the main causes of this disease.Studies have shown that Yangluo Tongbi recipe has the functions of reducing inflammation,repairing nerve function,improving hemorrheology,regulating growth factors,etc.Thus,further research on the etiology and pathogenesis of“collateral-loss and arterial-obstruction”of DPN and the mechanism of Yangluo Tongbi method have important clinical significance for improving the prevention and treatment level of DPN.

关 键 词：“络损脉痹” 糖尿病周围神经病变 病因病机 证候分析 临床实践 作用机理 理论探讨 

分 类 号：R587.1[医药卫生—内分泌]