温针灸联合穴位敷贴治疗膝骨性关节炎的效果及对临床症状改善、膝关节功能及炎症因子的影响  

Effect of needle warming moxibustion combined with acupoint application on knee osteoarthritis and its influence on clinical symptom improvement,knee function and inflammatory factors

作　　者：郑皖云 方芳 李侠 王继明[1] ZHENG Wanyun;FANG Fang;LI Xia(Lu'an Hospital of traditional Chinese medicine Rehabilitation Division,Lu'an Anhui 237000,China)

机构地区：[1]六安市中医院康复三科,安徽六安237000

出　　处：《四川中医》2024年第6期220-222,F0003,共4页Journal of Sichuan of Traditional Chinese Medicine

摘　　要：目的:探究温针灸联合穴位敷贴治疗膝骨性关节炎(KOA)的效果及对临床症状改善、膝关节功能及炎症因子的影响。方法:选取我院康复三科2021年1月到2023年3月收治的88例患者,按随机掷硬币法分为西药组和中医组,每组44例,西药组予以西药治疗,中医组在此基础上予以温针灸联合穴位敷贴治疗,观察两组临床疗效、中医证候积分、膝关节功能Lequesne量表评分、血清炎症因子[白细胞介素-1(IL-1)、肿瘤坏死因子-α(TNF-a)、C反应蛋白(CRP)]及不良反应发生情况。结果:中医组治疗总有效率显著高于西药组(P<0.05);治疗后,中医组关节疼痛、关节肿大及屈伸不利积分均低于西药组(P<0.05);治疗后,中医组疼痛不适、行走距离及日常活动评分均低于西药组(P<0.05);治疗后,中医组血清IL-1、TNF-α、CRP水平均低于西药组(P<0.05);两组用药不良反应比较无显著性差异(P>0.05)。结论:温针灸联合穴位敷贴治疗KOA安全有效,能明显缓解临床症状、改善膝关节功能,减轻机体炎症,值得在临床推广应用。ObjectiveTo explore the effect of needle warming moxibustion combined with acupoint application in the treatment of knee osteoarthritis(KOA)and its influence on clinical symptom improvement,knee function and inflammatory factors.Methods 88patients in department of rehabilitation division of our hospital from January 2021to March 2023were selected and divided into western medicine group and traditional Chinese medicine group by the random coin tossing method,with 44cases in each group.The western medicine group was given western medicine treatment,and the traditional Chinese medicine group was treated with needle warming moxibustion combined with acupoint application on this basis.The clinical efficacy,TCM syndromes scores,knee function Lequesne scale scores,serum inflammatory factors[interleukin-1(IL-1),tumor necrosis factor-α(TNF-a),C-reactive protein(CRP)]and occurrence of adverse reactions were observed in the two groups.Results The total effective rate of treatment in traditional Chinese medicine group was significantly higher than that in western medicine group(P<0.05).After treatment,the scores of joint pain,arthrocele and inhibited bending and stretching were lower in traditional Chinese medicine group than those in western medicine group(P<0.05).After treatment,the scores of pain discomfort,walking distance and daily activities in traditional Chinese medicine group were lower compared with those in western medicine group(P<0.05).The levels of serum IL-1,TNF-αand CRP in traditional Chinese medicine group after treatment were lower than those in western medicine group(P<0.05).There were no significant differences in adverse reactions between the two groups(P>0.05).Conclusion Needle warming moxibustion combined with acupoint application is safe and effective in the treatment of KOA,and it can significantly relieve the clinical symptoms,improve the knee function,relieve the body’s inflammation.

关 键 词：温针灸 穴位敷贴 膝骨性关节炎 膝关节功能 炎症因子 

分 类 号：R246.2[医药卫生—针灸推拿学]