母乳喂养对女性产后脂质代谢重塑的作用研究进展  

Research Progress of Effect of Breastfeeding on Postpartum Lipid Metabolism Remodeling in Women

作　　者：王艺[1] 刘岚[1] WANG Yi;LIU Lan(Department of Obstetrics,Women′s Hospital of Nanjing Medical University/Nanjing Women and Children′s Healthcare Hospital,Nanjing 210004,China)

机构地区：[1]南京医科大学附属妇产医院,南京市妇幼保健院产科,南京210004

出　　处：《医学综述》2024年第16期1971-1975,1983,共6页Medical Recapitulate

基　　金：江苏省妇幼保健协会科研课题(FYX202306)。

摘　　要：妊娠是一个需要充足能量和营养供应的生理过程,母体会发生一系列的代谢适应变化以满足胎儿生长发育需要,包括妊娠早期脂质大量合成、妊娠晚期母体的主要能量来源由糖代谢到脂质代谢的转变。这会给母体健康带来巨大挑战,这些生理过程往往伴随着母体胰岛素敏感性下降、内脏脂肪堆积、血脂升高等不利影响,此时产后哺乳这一生理过程显得尤为重要。母乳喂养在降低女性产后肥胖、降低血脂水平、减少代谢综合征等远期疾病发生风险方面具有重要作用,甚至能降低妊娠期伴妊娠糖尿病女性产后2型糖尿病的发生率,但母乳喂养给女性带来的益处仍未完全被挖掘,后续仍需深入探索。Pregnancy is a physiological process that requires adequate energy and nutrient supply,and a series of metabolic adaptation changes will occur in the mother′s body to meet the needs of fetal growth and development,including a large amount of lipid synthesis in the first trimester of pregnancy,and the transformation of the mother′s main energy source from glucose metabolism to lipid metabolism in the third trimester.This poses a huge challenge to the maternal health,as these physiological processes are often accompanied by adverse effects such as decreased maternal insulin sensitivity,accumulation of visceral fat,and increased blood lipids,thus the physiological process of postpartum breastfeeding is particularly important.Breastfeeding has been shown to play an important role in reducing postpartum obesity,lowering blood lipid levels,reducing the risk of long-term diseases such as metabolic syndrome,and even reducing the incidence of postpartum type 2 diabetes in women with gestational diabetes during pregnancy,but the benefits of breastfeeding for women have not yet been fully explored,and further exploration is still needed.

关 键 词：妊娠 哺乳 脂质代谢 

分 类 号：R714.256[医药卫生—妇产科学]