复方丹参注射液治疗妊娠高血压患者的临床效果及对妊娠结局的影响  

Clinical effect of Compound Danshen Injection in the treatment of patients with gestational hypertension and its influence on pregnancy outcomes

作　　者：徐曼 XU Man(Yuncheng County People’s Hospital,Shandong Province,Yuncheng 274700,China)

机构地区：[1]山东省郓城县人民医院,山东郓城274700

出　　处：《妇儿健康导刊》2024年第13期101-104,共4页JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE

摘　　要：目的 分析复方丹参注射液治疗妊娠高血压患者的临床效果及对妊娠结局的影响。方法 选取2019年3月至2023年2月郓城县人民医院收治的90例妊娠高血压患者作为研究对象,按照随机数字表法分为对照组(n=45)与观察组(n=45)。对照组采用硝苯地平缓释片治疗,观察组在对照组基础上采用复方丹参注射液治疗。比较两组临床疗效、临床指标、不良妊娠结局及并发症发生情况。结果 观察组临床总有效率为97.78%,高于对照组的71.11%,差异有统计学意义(P <0.05)。治疗后,观察组内皮素(ET)水平低于对照组,一氧化氮(NO)水平高于对照组,差异有统计学意义(P <0.05)。观察组不良妊娠结局及并发症总发生率为2.22%,低于对照组的20.00%,差异有统计学意义(P <0.05)。结论 复方丹参注射液治疗妊娠高血压可提高临床疗效,降低ET水平,提高NO水平,改善妊娠结局,减少并发症。Objective To analyze the clinical effect of Compound Danshen Injection in the treatment of patients with gestational hypertension and its influence on pregnancy outcomes.Methods A total of 90 patients with gestational hypertension in Yuncheng County People’s Hospital from March 2019 to February 2023 were selected as the study objects.All the patients were divided into the control group(n=45)and the observation group(n=45)according to the random number table method.The control group was treated with Nifedipine Sustained-Release Tablets,and the observation group was treated with Compound Danshen Injection on the basis of the control group.The clinical efficacy,clinical indicators,incidence of adverse pregnancy outcomes and complications were compared between the two groups.Results The total clinical effective rate of the observation group was 97.78%,which was higher than 71.11%of the control group,and the difference was statistically significant(P<0.05).After treatment,the level of endothelin(ET)in the observation group was lower than that in the control group,the level of nitric oxide(NO)was higher than that in the control group,and the differences were statistically significant(P<0.05).The total incidence of adverse pregnancy outcomes and complications in the observation group was 2.22%,which was lower than 20.00%in the control group,and the difference was statistically significant(P<0.05).Conclusion The treatment of Compound Danshen Injection in patients with gestational hypertension can improve the clinical efficacy,reduce the level of ET,increase the level of NO,improve the pregnancy outcomes,and reduce complications.

关 键 词：复方丹参注射液 妊娠高血压 妊娠结局 

分 类 号：R714.25[医药卫生—妇产科学]