针刺防治血管性痴呆作用机制研究进展  

Research Progress on Action Mechanism of Acupuncture in Preventing and Treating Vascular Dementia

作　　者：冉易霖 刘勇[2] 韩鹏[1] RAN Yilin;LIU Yong;HAN Peng(Heilongjiang University of Chinese Medicine,Harbin 150040,China;The First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150040,China)

机构地区：[1]黑龙江中医药大学,黑龙江哈尔滨150040 [2]黑龙江中医药大学附属第一医院,黑龙江哈尔滨150040

出　　处：《针灸临床杂志》2024年第6期99-102,共4页Journal of Clinical Acupuncture and Moxibustion

基　　金：黑龙江省自然科学基金面上项目,编号:H2016061;黑龙江省卫生健康委科研课题,编号:20232121020244;黑龙江中医药大学科研基金,编号:2019MS18。

摘　　要：VD是一种由于脑血管病变导致的认知功能障碍综合征,目前被认为是唯一有可能预防的痴呆类型。研究表明,针刺防治VD具有肯定的疗效,能够明显改善患者认知功能、学习和记忆能力等,且与口服药物治疗相比具有副作用小的优势,但其作用机制尚有待探讨。本研究梳理近年来针刺防治VD的相关文献,发现针刺可能通过改善炎症反应、氧化应激、中枢胆碱能神经通路障碍与中枢神经兴奋性毒性等作用机制对VD起治疗作用。VD is a cognitive dysfunction syndrome caused by cerebrovascular disease,and is currently considered the only possible type of dementia that can be prevented.Research has shown that acupuncture has a definite therapeutic effect on the prevention and treatment of VD,which can significantly improve patients' cognitive function,learning and memory abilities,and has the advantage of fewer side effects compared to oral medication.However,its action mechanism still needs to be explored.This study reviewed relevant literature on acupuncture for the prevention and treatment of VD in recent years,and it is found that acupuncture can treat VD through possible mechanisms including improving inflammatory response,oxidative stress,central cholinergic pathway disorders,and central nervous system excitatory toxicity.

关 键 词：血管性痴呆 针刺 作用机制 

分 类 号：R246.6[医药卫生—针灸推拿学]