轻度创伤性脑损伤的研究进展  

Recent advance in mild traumatic brain injury

作　　者：孙春晖 亓超逸 高敏 吴月鹏 Sun Chunhui;Qi Chaoyi;Gao Min;Wu Yuepeng(Department of Neurology,Second Affiliated Hospital of Shandong First Medical University,Tai'an 271000,China;Department of General Surgery,Tai'an Hospital of Traditional Chinese Medicine,Tai'an 271000,China)

机构地区：[1]山东第一医科大学第二附属医院神经内科,泰安271000 [2]泰安市中医医院普外科,泰安271000

出　　处：《中华神经医学杂志》2024年第6期618-623,共6页Chinese Journal of Neuromedicine

摘　　要：轻度创伤性脑损伤(mTBI)是头部遭受外力后发生的短暂性意识及记忆功能障碍,但神经功能学及神经影像学检查结果基本正常的一种创伤性疾病。目前,因临床表现轻微致早期识别诊断mTBI患者非常困难,传统的用于伤势较重患者的诊疗评估方式并不太适用于mTBI患者,故对mTBI的研究相对不足。本文现围绕mTBI的发病机制、辅助检查、治疗原则及其相关疾病等方面的研究进展进行综述,旨在为mTBI提供新的诊疗理论依据。Mild traumatic brain injury(mTBI)is a traumatic disease that has transient impairment of consciousness and memory function after an external force to the head with basically normal neurological function and neuroimaging examination results.At present,research on mTBI is insufficient,resulting from early diagnosed difficulty of mTBI patients(due to mild clinical manifestations)and not suitable traditional diagnosis and treatment evaluation methods.This article reviews the research progress in the pathogenesis,auxiliary examinations,treatment principles and related diseases of mTBI,aiming to provide new theoretical basis for diagnosis and treatment of mTBI.

关 键 词：颅脑损伤 轻度 慢性创伤性脑病 炎症反应 血脑屏障 细胞损伤 能量危机 

分 类 号：R651.15[医药卫生—外科学]