北京市某综合医院成人社区获得性肺炎病原学结果分析  

Analysis of the Etiological Results of Community-acquired Pneumonia in Adults in A General Hospital in Beijing

作　　者：姜巧巧[1] 郭政[1] 李利伟[1] Jiang Qiaoqiao;Guo Zheng;Li Liwei(Beijing Chuiyangliu Hospital,Beijing,100022,China)

机构地区：[1]北京市垂杨柳医院,北京100022

出　　处：《中国初级卫生保健》2024年第7期48-50,共3页Chinese Primary Health Care

摘　　要：目的:了解北京市某综合医院成人社区获得性肺炎的病原体分布情况,为临床诊治和疾病防控提供参考依据。方法:2018—2019年选取在北京市某综合医院感染科就诊的成人社区获得性肺炎患者,采集病例的痰液样本,采用多重实时荧光定量PCR检测方法对样本进行多种呼吸道病原体检测,分析呼吸道病原体在不同年龄段患者和不同季节中的检出情况。结果:330例社区获得性肺炎患者中,有286例患者检出呼吸道病原体,检出率为86.67%,其中检出单纯细菌感染、肺炎支原体感染、病毒感染和肺炎衣原体感染患者分别为98例、47例、16例和2例。在123例样本中检出混合病原体,检出率为37.27%。混合病原体感染中以细菌合并肺炎支原体最为多见,其次是细菌合并病毒感染。呼吸道病原体检出前3位依次为肺炎链球菌、肺炎支原体和流感嗜血杆菌。18~59岁年龄段患者肺炎支原体检出率明显高于≥60岁年龄段患者。结论:北京市某综合医院成人社区获得性肺炎患者呼吸道感染病原体以肺炎链球菌、肺炎支原体和流感嗜血杆菌为主,且混合感染率较高,临床上要重视混合病原体感染,并合理选择抗感染药物。OBJECTIVE To understand the pathogen distribution of adult community-acquired pneumonia(CAP)in a comprehen-sive hospital of Beijing,so as to provide basis for clinical diagnosis and treatment and disease prevention and control.METHODS The lower respiratory tract samples of 330 adult CAP patients who were treated in the Department of Infectious Diseases of a general hospital in Beijing from 2018 to 2019 were collected,and the samples were detected by multiple real-time PCR detection methods for a variety of respiratory pathogens,and the detection of respiratory pathogens in different ages and seasons was analyzed.RE-SULTS Among the samples of 330 adult patients with CAP,respiratory pathogens were detected in 286 cases,with a detection rate of 86.67%,of which 98 cases were detected with simple bacterial infection,47 cases with Mycoplasma pneumoniae infection,16 cas-es with viral infection and 2 cases with Chlamydia pneumoniae infection.Mixed pathogens were detected in 123 samples,with a de-tection rate of 37.27%.The mixed infection of bacteria and mycoplasma pneumoniae was the most common,followed by bacterial and viral infections.The top three respiratory pathogens were Streptococcus pneumoniae,mycoplasma and Haemophilus influenzae.The detection rate of Mycoplasma pneumoniae in patients aged 18~59 is significantly higher than that in patients aged≥60 years old.CONCLUSION The main pathogens of respiratory tract infection in adult CAP patients in a general hospital in Beijing are Strep-tococcus pneumoniae,Mycoplasma pneumoniae and Haemophilus influenzae,and the mixed infection rate of CAP is high.The clini-cal also must attach importance to the mixed pathogen infection and the reasonable choice anti-infection medicine.

关 键 词：综合医院 成人 社区获得性肺炎 病原学结果 

分 类 号：R563.1[医药卫生—呼吸系统]