河南省121例布鲁氏菌病未成年患者感染方式及临床特征分析  

Analysis of Infection Pattern and Clinical Characteristics of 121 Juvenile Brucellosis Cases in Henan

作　　者：余小娟 李亚飞 杜琰[1] Yu Xiaojuan;Li Yafei;Du Yan(Clinical Research Unit,Obstetrics and Gynecology Hospital of Fudan University,Shanghai,200011,China;不详)

机构地区：[1]复旦大学附属妇产科医院临床研究中心,上海200011 [2]河南省疾病预防控制中心传染病所,河南郑州450000

出　　处：《中国初级卫生保健》2024年第7期56-59,共4页Chinese Primary Health Care

基　　金：河南省医学科技攻关计划联合共建项目(LHGJ20220160)。

摘　　要：目的:分析河南省布鲁氏菌病(简称布病)未成年患者的感染方式及临床特征,为制定布病防控措施提供参考。方法:通过中国疾病预防控制信息系统和病例个案调查表,获取2023年1—6月河南省未成年布病患者信息,采用描述性流行病学方法对数据进行分析。结果:共获取了112例布病患者的完整信息,河南省未成年人布病发病率为0.414/10万,各年龄段均有发病,平均发病年龄为(8.74±5.21)岁,男性与女性患者比例为1.87∶1,无死亡病例。112例布病患者中,83.93%有动物接触史,其中饲养羊、食用畜产品为主要暴露方式,主要感染地点在家中。临床表现以急性期为主,发热为最常见症状,出现发热症状的患者占比达92.86%(104/112);其次为多汗、肌肉关节酸痛及乏力;肝肿大、脾肿大、淋巴结肿大及其他并发症的发生率较低。散居儿童、农民多汗和肌肉、关节酸痛的发生率比较,差异均有统计学意义(χ2值分别为11.49、9.84,P<0.05)。结论:河南省布病未成年患者各年龄段均有确诊,感染场所主要在家中,饲养及食用畜产品为主要的感染原因。应进一步加强布病防控综合措施,加强专项宣传和教育工作,规范养殖管理,降低布病未成年患者的发病率。OBJECTIVE To analyze the infection pattern and clinical characteristics of juvenile brucellosis cases in Henan province,and to provide specific evidence for developing brucellosis prevention and control measures.METHODS Data of juvenile brucellosis cases from January to June 2023 were obtained through the Chinese Disease Prevention and Control Information System and the case survey form,and analyzed through descriptive epidemiological methods.RESULTS A total of 112 cases with complete information were obtained,the incidence rate was 0.414/105,and cases were distributed at all age categories.The average age of onset morbidity was 8.74±5.21 years old,the male to female ratio was 1.87:1,and no death was reported.It showed that 83.93%of the cases had animal exposure history,among which raising sheep and eating animal products were the main exposures,and the main infection place was at home.Fever was the most common symptom(92.86%,104/112),followed by hyperhidrosis,muscle and joint pain and fatigue.The incidences of liver enlargement,spleen enlargement,lymph node enlargement and other complications were low.There were significant differences in the incidences of hyperhidrosis and muscle and joint soreness between scattered children and farmers(χ2=11.49,9.84,P<0.05).CONCLUSION Juvenile brucellosis is diagnosed at all age categories in Henan Province.The main infection place is at home,and the main infection cause is feeding and eating animal products.It is necessary to further strengthen comprehensive measures of brucellosis prevention and control,promote relevant health campaign and education,standardize breeding management,so as to reduce the incidence of brucellosis in juveniles.

关 键 词：布鲁氏菌病 未成年人 感染模式 临床症状 预防 

分 类 号：R378.5[医药卫生—病原生物学]