三频谱点的人体细胞内外液研究方法  

Study of intracellular and extracellular fluids in the human body with three spectral point

作　　者：李勇[1] 梁竹关[1] 王元元 Li Yong;Liang Zhuguan;Wang Yuanyuan(School of Information Science&Engineering,Yunnan University,Kunming 650500,China)

机构地区：[1]云南大学信息学院,昆明650500

出　　处：《国外电子测量技术》2024年第7期75-82,共8页Foreign Electronic Measurement Technology

基　　金：国家自然科学基金(62266049)项目资助。

摘　　要：通过对人体细胞内液和细胞外液这两个参数的特征分析可以预测或诊断人体的某些疾病。应用传统的生物电阻抗谱分析法计算这两个值时,需要用到几百甚至几千个频率点的人体生物电阻抗数据,数据的采集和处理都极为复杂。基于Cole-Cole理论提出了三频谱点法与Moissl方程相结合的人体细胞内、外液研究方法。该方法只需要采集和应用3个频率点的生物电阻抗值,就可以提取出生物电阻抗参数,进一步计算出细胞内液和细胞外液。实验结果表明,方法与常用的生物电阻抗谱分析法得到的结果相吻合,且采集数据和处理数据耗时仅为传统方法的12.73%。Through the characterization of the two parameters of intracellular and extracellular fluids,it is possible to predict or diagnose certain diseases in the human body.When calculating these two values using traditional bioelectrical impedance spectroscopy,human bioelectrical impedance data of hundreds or even thousands of frequency points is required,and the data collection and processing are extremely complex.Based on the Cole-Cole theory,this paper proposes a method for the study of intracellular and extracellular fluids by combining the three-spectral point method and the Moissl equation.In this method,only three frequency points of bioelectrical impedance values need to be collected and applied,the bioelectrical impedance parameters can be extracted,and the intracellular and extracellular fluids can be further calculated.The results verify that the results obtained by this method are consistent with these gained by the commonly used bioelectrical impedance spectroscopy method,and the time taken to collect and process the data is only 12.73%of that of the traditional method.

关 键 词：Cole-Cole理论 生物电阻抗 三频谱点法 人体细胞内外液 Moissl方程 

分 类 号：R318[医药卫生—生物医学工程] TN98[医药卫生—基础医学]